(Q44088576)

29 November 2017

Novel 20-carbonate linked prodrugs of camptothecin and 9-aminocamptothecin designed for activation by tumour-associated plasmin (English)

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29 November 2017

Franciscus M H de Groot

1

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29 November 2017

Guuske F Busscher

2

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29 November 2017

René W M Aben

3

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29 November 2017

Hans W Scheeren

4

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29 November 2017

language of work or name

English

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publication date

1 September 2002

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29 November 2017

6

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Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

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29 November 2017

12

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29 November 2017

2371-2376

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29 November 2017

17

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Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

29 November 2017

1 reference

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7 January 2021

Modulation of camptothecin analogs in the treatment of cancer: a review

1 reference

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7 January 2021

DNA topoisomerase I and II in cancer chemotherapy: update and perspectives

1 reference

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7 January 2021

Topoisomerase I poisons and suppressors as anticancer drugs

1 reference

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7 January 2021

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

1 reference

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7 January 2021

Receptor-mediated and enzyme-dependent targeting of cytotoxic anticancer drugs

1 reference

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7 January 2021

Drug-targeting strategies in cancer therapy

1 reference

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7 January 2021

Anticancer prodrugs for application in monotherapy: targeting hypoxia, tumor-associated enzymes, and receptors

1 reference

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7 January 2021

Clinical applications of the camptothecins.

1 reference

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7 January 2021

A phase II study of 9-aminocamptothecin in advanced non-small-cell lung cancer

1 reference

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7 January 2021

Phase II trial of aminocamptothecin (9-AC/DMA) in patients with advanced squamous cell head and neck cancer

1 reference

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7 January 2021

A phase II study of 9-aminocamptothecin in patients with refractory breast cancer

1 reference

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7 January 2021

Phase II trial of 9-aminocamptothecin administered as a 72-hour continuous infusion in metastatic colorectal carcinoma

1 reference

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7 January 2021

Protease-activated “prodrugs” for cancer chemotherapy

1 reference

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7 January 2021

Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard

1 reference

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7 January 2021

Plasmin-activated prodrugs for cancer chemotherapy. 2. Synthesis and biological activity of peptidyl derivatives of doxorubicin

1 reference

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7 January 2021

Synthesis and biological evaluation of novel prodrugs of anthracyclines for selective activation by the tumor-associated protease plasmin

1 reference

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7 January 2021

Synthesis and biological evaluation of 2'-carbamate-linked and 2'-carbonate-linked prodrugs of paclitaxel: selective activation by the tumor-associated protease plasmin

1 reference

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7 January 2021

Design and synthesis of water-soluble glucuronide derivatives of camptothecin for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT)

1 reference

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7 January 2021

Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin

1 reference

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7 January 2021

Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

Role of erythrocytes and serum proteins in the kinetic profile of total 9-amino-20(S)-camptothecin in humans

1 reference

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7 January 2021

Alkyl esters of camptothecin and 9-nitrocamptothecin: synthesis, in vitro pharmacokinetics, toxicity, and antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

20-O-acylcamptothecin derivatives: evidence for lactone stabilization.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

Camptothecin-20-PEG ester transport forms: the effect of spacer groups on antitumor activity

1 reference

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7 January 2021

Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

Polymer-bound camptothecin: initial biodistribution and antitumour activity studies

1 reference

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7 January 2021

Elongated multiple electronic cascade and cyclization spacer systems in activatible anticancer prodrugs for enhanced drug release

1 reference

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7 January 2021

A novel connector linkage applicable in prodrug design

1 reference

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7 January 2021

Antineoplastic Agents from Plants

1 reference

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7 January 2021

Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900388-8

7 January 2021

10.1016/S0960-894X(02)00388-8

Identifiers

DOI

1 reference

29 November 2017

1 reference