(Q44090416)

29 November 2017

title

Limited induction of torsade de pointes by terikalant and erythromycin in an in vivo model (English)

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29 November 2017

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András Farkas

1

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author name string

Susan J Coker

series ordinal

2

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29 November 2017

language of work or name

English

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publication date

1 August 2002

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European Journal of Pharmacology

29 November 2017

published in

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29 November 2017

volume

449

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29 November 2017

issue

1-2

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29 November 2017

page(s)

143-153

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Potassium and calcium current blocking properties of the novel antiarrhythmic agent H 345/52: implications for proarrhythmic potential

29 November 2017

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Cellular and Ionic Mechanisms Underlying Erythromycin-Induced Long QT Intervals and Torsade de Pointes

7 January 2021

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Glibenclamide does not prevent action potential shortening induced by ischemia in anesthetized rabbits but reduces ischemia-induced arrhythmias

7 January 2021

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A model of myocardial ischemia for the simultaneous assessment of electrophysiological changes and arrhythmias in intact rabbits

7 January 2021

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Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsade de pointes

7 January 2021

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Erythromycin blocks the rapid component of the delayed rectifier potassium current and lengthens repolarization of guinea pig ventricular myocytes

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Effects of class III antiarrhythmic agents in an in vitro rabbit model of spontaneous torsades de pointe

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Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

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Cardiac actions of erythromycin: influence of female sex.

7 January 2021

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Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart

7 January 2021

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Female gender as a risk factor for drug-induced cardiac arrhythmias: evaluation of clinical and experimental evidence

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Evaluation of antiarrhythmic drugs on defibrillation energy requirements in dogs. Sodium channel block and action potential prolongation

7 January 2021

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7 January 2021

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Proarrhythmic effects of intravenous quinidine, amiodarone, D-sotalol, and almokalant in the anesthetized rabbit model of torsade de pointes

7 January 2021

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Suppression of erythromycin-induced early afterdepolarizations and torsade de pointes ventricular tachycardia by mexiletine

7 January 2021

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Prolongation of cardiac refractory times in man by clofilium phosphate, a new antiarrhythmic agent

7 January 2021

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Pharmacodynamic analysis of the electrocardiographic interaction between disopyramide and erythromycin in rats

7 January 2021

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7 January 2021

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Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic

7 January 2021

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Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia

7 January 2021

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Electrocardiographic and clinical predictors of torsades de pointes induced by almokalant infusion in patients with chronic atrial fibrillation or flutter: a prospective study

7 January 2021

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Clofilium in the isolated perfused rabbit heart: a new model to study proarrhythmia induced by class III antiarrhythmic drugs

7 January 2021

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Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT. European Myocardial Infarct Amiodarone Trial Investigators

7 January 2021

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Mechanism of action potential prolongation by RP 58866 and its active enantiomer, terikalant. Block of the rapidly activating delayed rectifier K+ current, IKr.

7 January 2021

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Selectivity of class-III antiarrhythmic action of clofilium in guinea pig ventricular myocytes

7 January 2021

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Potentiation of halofantrine-induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine

7 January 2021

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Nonselective I(Kr)-blockers do not induce torsades de pointes in the anesthetized rabbit during alpha1-adrenoceptor stimulation

7 January 2021

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Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits

7 January 2021

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Ionic basis of the differential effects of intravenous anesthetics on erythromycin-induced prolongation of ventricular repolarization in the guinea pig heart

7 January 2021

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Dose-ranging studies of clofilium, an antiarrhythmic quaternary ammonium

7 January 2021

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Selective IK blockade as an antiarrhythmic mechanism: effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts

7 January 2021

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Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome

7 January 2021

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Antiarrhythmic drugs, clofilium and cibenzoline are potent inhibitors of glibenclamide-sensitive K+ currents in Xenopus oocytes

7 January 2021

1 reference

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Terikalant, an inward-rectifier potassium channel blocker, does not abolish the cardioprotection induced by ischemic preconditioning in the rat

7 January 2021

1 reference

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The min K channel underlies the cardiac potassium current IKs and mediates species-specific responses to protein kinase C.

7 January 2021

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The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion

7 January 2021

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Comparative Study of the Effects of Erythromycin and Roxithromycin on Action Potential Duration and Potassium Currents in Canine Purkinje Fibers and Rabbit Myocardium

7 January 2021

1 reference

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Kinetics of rate-dependent shortening of action potential duration in guinea-pig ventricle; effects of IK1 and IKr blockade

7 January 2021

1 reference

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Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901992-1

10.1016/S0014-2999(02)01992-1

7 January 2021

Identifiers

DOI

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29 November 2017

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