(Q44104444)

29 November 2017

title

XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis (English)

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29 November 2017

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Bratton SB

1

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29 November 2017

Lewis J

2

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29 November 2017

Butterworth M

3

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29 November 2017

Duckett CS

4

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29 November 2017

Cohen GM

5

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29 November 2017

language of work or name

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1 September 2002

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Cell Death & Differentiation

29 November 2017

published in

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29 November 2017

volume

9

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29 November 2017

issue

9

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29 November 2017

page(s)

881-892

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Caspases: the executioners of apoptosis

29 November 2017

cites work

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Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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Caspase-9 and APAF-1 form an active holoenzyme

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Caspase-9 can be activated without proteolytic processing

21 January 2018

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Structural basis for the inhibition of caspase-3 by XIAP

21 January 2018

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NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

21 January 2018

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NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP

21 January 2018

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X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes

21 January 2018

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A single BIR domain of XIAP sufficient for inhibiting caspases

21 January 2018

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Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

21 January 2018

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21 January 2018

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

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DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9

21 January 2018

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Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

21 January 2018

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21 January 2018

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Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

21 January 2018

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X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling

21 January 2018

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Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

21 January 2018

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Selective activation of JNK1 is necessary for the anti-apoptotic activity of hILP.

21 January 2018

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

21 January 2018

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21 January 2018

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Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

21 January 2018

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Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 January 2018

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Structural basis of IAP recognition by Smac/DIABLO

21 January 2018

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

Characterization of XIAP-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

inferred from DOI database lookup

7 January 2021

based on heuristic

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401069

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CDD.4401069

1 reference

29 November 2017

1 reference