(Q44115022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

Structural evidence that propofol stabilizes different GABA(A) receptor states at potentiating and activating concentrations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Daniel B Williams

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Myles H Akabas

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

English

0 references

publication date

1 September 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

page(s)

7417-7424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

Benzodiazepines do not modulate desensitization of recombinant alpha1beta2gamma2 GABA(A) receptors.

12 November 2019

cites work

1 reference

12 December 2020

How fast does the gamma-aminobutyric acid receptor channel open? Kinetic investigations in the microsecond time region using a laser-pulse photolysis technique

1 reference

12 December 2020

General anaesthetic actions on ligand-gated ion channels

1 reference

12 December 2020

Agonist gating and isoflurane potentiation in the human gamma-aminobutyric acid type A receptor determined by the volume of a second transmembrane domain residue.

1 reference

12 December 2020

Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors

1 reference

12 December 2020

The general anesthetic propofol slows deactivation and desensitization of GABA(A) receptors.

1 reference

12 December 2020

Propofol increases agonist efficacy at the GABA(A) receptor.

1 reference

12 December 2020

Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures

1 reference

12 December 2020

Relocation of internal bound water in bacteriorhodopsin during the photoreaction of M at low temperatures: an FTIR study

1 reference

12 December 2020

Water and bacteriorhodopsin: structure, dynamics, and function

1 reference

12 December 2020

Benzodiazepines induce a conformational change in the region of the gamma-aminobutyric acid type A receptor alpha(1)-subunit M3 membrane-spanning segment.

1 reference

12 December 2020

Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

1 reference

12 December 2020

General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility

1 reference

12 December 2020

Anesthetics and ion channels: molecular models and sites of action

1 reference

12 December 2020

Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase

1 reference

12 December 2020

Predictability of weak binding from X-ray crystallography: inhaled anesthetics and myoglobin

1 reference

12 December 2020

Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment

1 reference

12 December 2020

Microsecond exchange of internal water molecules in bacteriorhodopsin

1 reference

12 December 2020

Anesthetic stabilization of protein intermediates: myoglobin and halothane

1 reference

12 December 2020

Dominant gating governing transient GABA(A) receptor activity: a first latency and Po/o analysis.

1 reference

12 December 2020

Evidence for distinct conformations of the two alpha 1 subunits in diazepam-bound GABA(A) receptors

1 reference

12 December 2020

Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists

1 reference

12 December 2020

Kinetic properties and regulation of GABAA receptor channels

1 reference

12 December 2020

Gating scheme for single GABA-activated Cl- channels determined from stability plots, dwell-time distributions, and adjacent-interval durations

1 reference

12 December 2020

Kinetics of the reaction of p-chloromercuribenzoate with the sulfhydryl groups of glutathione, 2-mercaptoethanol, and phosphorylase b

1 reference

12 December 2020

Hydrogen exchange and structural dynamics of proteins and nucleic acids

1 reference

12 December 2020

Molecular and cellular mechanisms of general anaesthesia

1 reference

12 December 2020

Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture.

1 reference

12 December 2020

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

1 reference

12 December 2020

Desensitized states prolong GABAA channel responses to brief agonist pulses.

1 reference

12 December 2020

Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits.

1 reference

12 December 2020

Modulation of the GABAA receptor by propofol is independent of the gamma subunit.

1 reference

12 December 2020

Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution.

1 reference

12 December 2020

Acetylcholine receptor channel imaged in the open state

1 reference

12 December 2020

How quickly can GABAA receptors open?

1 reference

12 December 2020

Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit

1 reference

12 December 2020

Direct evidence for diazepam modulation of GABAA receptor microscopic affinity.

1 reference

12 December 2020

Alpha subunit isoform influences GABA(A) receptor modulation by propofol

1 reference

12 December 2020

Distinct loci mediate the direct and indirect actions of the anesthetic etomidate at GABA(A) receptors.

1 reference

12 December 2020

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

1 reference

12 December 2020

The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

1 reference

12 December 2020

Propofol and other intravenous anesthetics have sites of action on the gamma-aminobutyric acid type A receptor distinct from that for isoflurane.

1 reference

12 December 2020

The role of the GABA(A) receptor alpha1 subunit N-terminal extracellular domain in propofol potentiation of chloride current.

1 reference

12 December 2020

Modulatory and direct effects of propofol on recombinant GABAA receptors expressed in xenopus oocytes: influence of alpha- and gamma2-subunits.

1 reference

12 December 2020

Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor?

1 reference

12 December 2020

Substituted-cysteine accessibility method

1 reference

12 December 2020

Defining affinity with the GABAA receptor.

1 reference

12 December 2020

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

1 reference

12 December 2020

Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography

1 reference

12 December 2020

10.1523/JNEUROSCI.22-17-07417.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12196563%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference