(Q44119076)

30 November 2017

title

P21 functions to maintain quiescence of p27-deficient hepatocytes (English)

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30 November 2017

Angela L Tyner

5

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author name string

Young Hye Kwon

1

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30 November 2017

Aleksandra Jovanovic

2

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30 November 2017

Michael S Serfas

3

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30 November 2017

Hiroaki Kiyokawa

4

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30 November 2017

language of work or name

English

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publication date

28 August 2002

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Journal of Biological Chemistry

30 November 2017

published in

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30 November 2017

volume

277

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30 November 2017

issue

44

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30 November 2017

page(s)

41417-41422

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p21--negative regulator of the cell cycle

30 November 2017

cites work

1 reference

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New functional activities for the p21 family of CDK inhibitors

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

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p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

21 January 2018

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The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development.

21 January 2018

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The lack of a functional p21(WAF1/CIP1) gene ameliorates progression to chronic renal failure

21 January 2018

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

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Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

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Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

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Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

21 January 2018

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p27(Kip1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer.

21 January 2018

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21 January 2018

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21 January 2018

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The Mitochondrial Permeability Transition Augments Fas-induced Apoptosis in Mouse Hepatocytes

21 January 2018

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Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes

21 January 2018

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

21 January 2018

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Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination

21 January 2018

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Negative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1).

21 January 2018

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Cell attachment to the extracellular matrix induces proteasomal degradation of p21(CIP1) via Cdc42/Rac1 signaling

21 January 2018

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The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation

21 January 2018

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Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation

21 January 2018

1 reference

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Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

21 January 2018

1 reference

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A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

21 January 2018

1 reference

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CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice

21 January 2018

1 reference

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Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells

21 January 2018

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AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

21 January 2018

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Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development

21 January 2018

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p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

21 January 2018

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Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

21 January 2018

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Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity

21 January 2018

1 reference

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Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

21 January 2018

1 reference

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Loss of p27(Kip1) enhances the transplantation efficiency of hepatocytes transferred into diseased livers

21 January 2018

1 reference

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Advances in hepatocyte transplantation: a myth becomes reality

21 January 2018

1 reference

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Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M203388200

1 reference

30 November 2017

1 reference