(Q44120568)

English

Two-year toxicity and carcinogenicity studies in B(6)C(3)F(1) mice with 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent

scientific article published in September 2002

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scholarly article

1 reference

Europe PubMed Central

30 November 2017

Two-year toxicity and carcinogenicity studies in B(6)C(3)F(1) mice with 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent (English)

1 reference

Europe PubMed Central

30 November 2017

4

object named as

Fatih M Uckun

1 reference

Europe PubMed Central

30 November 2017

author name string

Osmond J D'Cruz

1

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Europe PubMed Central

30 November 2017

Douglas Erbeck

2

1 reference

Europe PubMed Central

30 November 2017

Barbara Waurzyniak

3

1 reference

Europe PubMed Central

30 November 2017

language of work or name

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publication date

1 September 2002

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Europe PubMed Central

30 November 2017

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Europe PubMed Central

30 November 2017

179

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30 November 2017

1-2

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Europe PubMed Central

30 November 2017

61-77

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Europe PubMed Central

30 November 2017

Molecular genotoxicity profiles of apoptosis-inducing vanadocene complexes

1 reference

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7 January 2021

based on heuristic

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Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900319-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Short-Term (13-week) toxicity study of 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent, in B6C3F1 mice

1 reference

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Lack of adverse effects on fertility of female CD-1 mice exposed to repetitive intravaginal gel-microemulsion formulation of a dual-function anti-HIV agent: aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07).

1 reference

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7 January 2021

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Gel-microemulsions as vaginal spermicides and intravaginal drug delivery vehicles

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900319-0

7 January 2021

based on heuristic

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Structural requirements for potent human spermicidal activity of dual-function aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07)

1 reference

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7 January 2021

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Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm

1 reference

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7 January 2021

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Aryl phosphate derivatives of bromo-methoxy-azidothymidine are dual-function spermicides with potent anti-human immunodeficiency virus

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of subchronic (13-week) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound whi-07) in B(6)C(3)F(1) mice.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term assays for carcinogenicity

1 reference

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7 January 2021

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Synthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5'-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agents

1 reference

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A submicron lipid emulsion coated with amphipathic polyethylene glycol for parenteral administration of paclitaxel (Taxol)

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Nonneoplastic lesions of the ovary in Fischer 344 rats and B6C3F1 mice

1 reference

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Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group

1 reference

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Mouse strains for chemical carcinogenicity studies: overview of a workshop

1 reference

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7 January 2021

based on heuristic

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The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

1 reference

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7 January 2021

based on heuristic

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Variability in the rates of some common naturally occurring tumors in Fischer 344 rats and (C57BL/6N x C3H/HeN)F1 (B6C3F1) mice.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Hematologic toxicity of AZT and ddC administered as single agents and in combination to rats and mice

1 reference

https://api.crossref.org/works/10.1016%2FS0300-483X%2802%2900319-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Prophylactic contraceptives for HIV/AIDS

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neoplastic and Nonneoplastic Lesions in Aging (C57BL/6N × C3H/HeN)F1 (B6C3F1) Mice2

1 reference

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The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system

1 reference

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Identifiers

10.1016/S0300-483X(02)00319-0

1 reference

Europe PubMed Central

30 November 2017

1 reference

Europe PubMed Central

30 November 2017

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