(Q44125037)

30 November 2017

title

Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease (English)

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30 November 2017

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Bernhard Landwehrmeyer

2

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30 November 2017

Johannes Schiefer

1

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30 November 2017

Hans-Gerd Lüesse

3

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30 November 2017

Arne Sprünken

4

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Christiane Puls

5

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30 November 2017

Anna Milkereit

6

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30 November 2017

Eva Milkereit

7

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Christoph M Kosinski

8

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30 November 2017

language of work or name

English

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publication date

1 July 2002

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30 November 2017

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30 November 2017

volume

17

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30 November 2017

issue

4

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30 November 2017

page(s)

748-757

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

30 November 2017

cites work

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Toward understanding the molecular pathology of Huntington's disease.

21 January 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene

21 January 2018

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

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Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?

21 January 2018

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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

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Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

21 January 2018

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Mutant huntingtin enhances excitotoxic cell death.

21 January 2018

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Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

21 January 2018

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Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory

21 January 2018

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The pharmacology and mechanism of action of riluzole

21 January 2018

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Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

21 January 2018

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Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes

21 January 2018

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Intranuclear inclusions in subtypes of striatal neurons in Huntington's disease transgenic mice

21 January 2018

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Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.

21 January 2018

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Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons.

21 January 2018

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Evaluation of R6/2 HD transgenic mice for therapeutic studies in Huntington's disease: behavioral testing and impact of diabetes mellitus

21 January 2018

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Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

21 January 2018

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Riluzole therapy in Huntington's disease (HD).

21 January 2018

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

21 January 2018

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Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

21 January 2018

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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

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Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease

21 January 2018

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

21 January 2018

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Aging, energy, and oxidative stress in neurodegenerative diseases.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MDS.10229

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30 November 2017

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