(Q43676817)

25 November 2017

Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease (English)

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25 November 2017

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1

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25 November 2017

Ferrante RJ

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25 November 2017

Huang HM

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25 November 2017

Dedeoglu A

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25 November 2017

Park L

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25 November 2017

Ferrante KL

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25 November 2017

Kwon J

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25 November 2017

Borchelt DR

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25 November 2017

Ross CA

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25 November 2017

Gibson GE

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25 November 2017

Beal MF

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25 November 2017

1 July 2001

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25 November 2017

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25 November 2017

50

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25 November 2017

112-117

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25 November 2017

1

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Energetics in the pathogenesis of neurodegenerative diseases

25 November 2017

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Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy

21 January 2018

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Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

21 January 2018

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Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

21 January 2018

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Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

21 January 2018

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Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

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Treatment of congenital lactic acidosis with dichloroacetate

21 January 2018

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Stabilization of the pyruvate dehydrogenase E1alpha subunit by dichloroacetate

21 January 2018

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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

21 January 2018

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The role of cytosolic free calcium in the regulation of pyruvate dehydrogenase in synaptosomes.

21 January 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

21 January 2018

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Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

21 January 2018

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Effects of dichloroacetate in three patients with MELAS.

21 January 2018

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Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

21 January 2018

1 reference

Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy

21 January 2018

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Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse

21 January 2018

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Improvement of lesions shown on MRI and CT scan by administration of dichloroacetate in patients with Leigh syndrome

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/ANA.1085

1 reference

release_ios5vdj4ynegjgr2ln3ocmodvi

25 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/ios5vdj4ynegjgr2ln3ocmodvi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference