(Q44132425)

30 November 2017

title

Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent (English)

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30 November 2017

4

Gregory J Gores

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30 November 2017

Nathan W Werneburg

1

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30 November 2017

M Eugenia Guicciardi

series ordinal

2

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30 November 2017

Steven F Bronk

series ordinal

3

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30 November 2017

publication date

1 October 2002

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American Journal of Physiology - Gastrointestinal and Liver Physiology

30 November 2017

published in

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30 November 2017

volume

283

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30 November 2017

issue

4

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30 November 2017

page(s)

G947-56

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Lysosomal involvement in apoptosis

30 November 2017

cites work

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

21 January 2018

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Organelle-specific initiation of cell death pathways

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Mitochondria and apoptosis

21 January 2018

1 reference

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cathepsin D targeted by acid sphingomyelinase-derived ceramide

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Ceramide as an activator lipid of cathepsin D.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Tumor necrosis factor receptor-mediated signaling pathways

21 January 2018

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Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Alterations in the structure, physicochemical properties, and pH of hepatocyte lysosomes in experimental iron overload

21 January 2018

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Lysosomal heterogeneity between and within cells with respect to resistance against oxidative stress.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Sphingolipids in mammalian cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cellular injury induced by oxidative stress is mediated through lysosomal damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cathepsins as effector proteases in hepatocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Caspase activation: the induced-proximity model

21 January 2018

1 reference

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Involvement of FAN in TNF-induced apoptosis

21 January 2018

1 reference

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Spectroscopic study of the activation and oligomerization of the channel-forming toxin aerolysin: identification of the site of proteolytic activation.

21 January 2018

1 reference

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Tumor necrosis factor receptor and Fas signaling mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Lysosomal destabilization in p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Delayed oxidant-induced cell death involves activation of phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00151.2002

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00151.2002

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30 November 2017

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