(Q44132582)

30 November 2017

Exogenous smac induces competence and permits caspase activation in sympathetic neurons (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

author name string

Mohanish Deshmukh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

Chunying Du

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

Xiaodong Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

Eugene M Johnson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 September 2002

1 reference

30 November 2017

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

page(s)

8018-8027

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

12 May 2020

cites work

1 reference

12 December 2020

Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2.

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12 December 2020

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

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12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

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12 December 2020

The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

Biochemical pathways of caspase activation during apoptosis

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12 December 2020

Studies on the mechanisms and kinetics of apoptosis induced by microinjection of cytochrome c in rat kidney tubule epithelial cells (NRK-52E)

1 reference

12 December 2020

Staurosporine-induced neuronal death: multiple mechanisms and methodological implications

1 reference

12 December 2020

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

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12 December 2020

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

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12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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12 December 2020

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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12 December 2020

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

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12 December 2020

Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons

1 reference

12 December 2020

The biochemistry of apoptosis

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12 December 2020

Apoptosis in the nervous system

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12 December 2020

Akt regulates cell survival and apoptosis at a postmitochondrial level

1 reference

12 December 2020

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 reference

12 December 2020

Structural basis of IAP recognition by Smac/DIABLO

1 reference

12 December 2020

Apoptosis in neurodegenerative disorders

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12 December 2020

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

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12 December 2020

Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.

1 reference

12 December 2020

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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12 December 2020

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

1 reference

12 December 2020

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

1 reference

12 December 2020

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

1 reference

12 December 2020

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

1 reference

12 December 2020

Mechanisms of caspase activation and inhibition during apoptosis

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12 December 2020

Generation and characterization of Smac/DIABLO-deficient mice.

1 reference

12 December 2020

Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium

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12 December 2020

Caspases in ischaemic brain injury and neurodegenerative disease

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12 December 2020

Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development.

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12 December 2020

The death programme in cultured sympathetic neurones can be suppressed at the posttranslational level by nerve growth factor, cyclic AMP, and depolarization

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12 December 2020

Cell death during development of the nervous system

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12 December 2020

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

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12 December 2020

cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor

1 reference

12 December 2020

Potassium concentration and number of neurons in cultures of dissociated ganglia

1 reference

12 December 2020

Techniques in the tissue culture of rat sympathetic neurons

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12 December 2020

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

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12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

12 December 2020

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

1 reference

12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

12 December 2020

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

1 reference

12 December 2020

Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons.

1 reference

12 December 2020

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

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12 December 2020

Involvement of caspases in sympathetic neuron apoptosis

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12 December 2020

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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12 December 2020

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

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12 December 2020

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

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12 December 2020

Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.

1 reference

12 December 2020

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

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12 December 2020

IAP family proteins--suppressors of apoptosis

1 reference

12 December 2020

10.1523/JNEUROSCI.22-18-08018.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758081&resulttype=core&format=json

12 May 2020

1 reference