(Q44133461)

30 November 2017

title

TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation (English)

1 reference

Target of rapamycin homolog CELE_B0261.2

30 November 2017

main subject

Caenorhabditis elegans

0 references

1 reference

GOA release 2020-03-11

author name string

Xiaomeng Long

1

1 reference

30 November 2017

Carmen Spycher

2

1 reference

30 November 2017

Z Stanley Han

3

1 reference

30 November 2017

Ann M Rose

4

1 reference

30 November 2017

Fritz Müller

5

1 reference

30 November 2017

Joseph Avruch

6

1 reference

30 November 2017

language of work or name

English

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publication date

1 September 2002

1 reference

30 November 2017

1 reference

30 November 2017

volume

12

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30 November 2017

issue

17

1 reference

30 November 2017

page(s)

1448-1461

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

30 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

TOR controls translation initiation and early G1 progression in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Target of rapamycin proteins and their kinase activities are required for meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The p70 S6 kinase integrates nutrient and growth signals to control translational capacity.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

PHAS/4E-BPs as regulators of mRNA translation and cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The mRNA 5' cap-binding protein eIF4E and control of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

A protein conjugation system essential for autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Alpha 4 associates with protein phosphatases 2A, 4, and 6

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The Arabidopsis homolog of yeast TAP42 and mammalian alpha4 binds to the catalytic subunit of protein phosphatase 2A and is induced by chilling.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The TOR signal transduction cascade controls cellular differentiation in response to nutrients

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Arresting development arrests aging in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

FAT: a novel domain in PIK-related kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Distribution and transport of cholesterol in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Multiple isoforms of eukaryotic protein synthesis initiation factor 4E in Caenorhabditis elegans can distinguish between mono- and trimethylated mRNA cap structures

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Functional characterization of five eIF4E isoforms in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Regulation of translation initiation by FRAP/mTOR

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Genetic control of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Akt/protein kinase B promotes organ growth in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901091-6

7 January 2021

10.1016/S0960-9822(02)01091-6

Identifiers

DOI

1 reference

30 November 2017

1 reference