(Q44134117)

English

The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.

scientific article published in September 2002

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13 November 2019

The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit (English)

1 reference

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13 November 2019

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13 November 2019

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Isabelle Ader

1

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13 November 2019

Catherine Muller

2

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13 November 2019

Jacques Bonnet

3

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13 November 2019

Elizabeth Cohen-Jonathan

5

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13 November 2019

Bernard Salles

6

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13 November 2019

Christine Toulas

7

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13 November 2019

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1 September 2002

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13 November 2019

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13 November 2019

21

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13 November 2019

42

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13 November 2019

6471-6479

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13 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205838

0 references

Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms.

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Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin

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Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor

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The promoters for human DNA-PKcs (PRKDC) and MCM4: divergently transcribed genes located at chromosome 8 band q11

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Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

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Characterization of the promoter region, first ten exons and nine intron-exon boundaries of the DNA-dependent protein kinase catalytic subunit gene, DNA-PKcs (XRCC7).

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Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells

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BTF3 is a potential new substrate of protein kinase CK2

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Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity

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21 January 2018

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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21 January 2018

Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining

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21 January 2018

36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO

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UV sensitivity and impaired nucleotide excision repair in DNA-dependent protein kinase mutant cells.

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Human normal peripheral blood B-lymphocytes are deficient in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku86 protein

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21 January 2018

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

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21 January 2018

High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons

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21 January 2018

Nuclear and cytoplasmic localization of different basic fibroblast growth factor species

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21 January 2018

Induction of the transcriptional repressor Yin Yang-1 by vascular cell injury. Autocrine/paracrine role of endogenous fibroblast growth factor-2

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21 January 2018

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

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Intracellular association of FGF-2 with the ribosomal protein L6/TAXREB107

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Increased expression of DNA-dependent protein kinase confers resistance to adriamycin

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The DNA-dependent protein kinase

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Basic fibroblast growth factor activates serum response factor gene expression by multiple distinct signaling mechanisms

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Nuclear accumulation of fibroblast growth factor receptors in human glial cells--association with cell proliferation.

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Gene expression of fibroblast growth factors in human gliomas and meningiomas: demonstration of cellular source of basic fibroblast growth factor mRNA and peptide in tumor tissues

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Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.

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Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

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The DNA-activated protein kinase -- DNA-PK

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A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

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Role of protein kinase CK2 in phosphorylation nucleosomal proteins in relation to transcriptional activity

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FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2

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The SMRT corepressor is a target of phosphorylation by protein kinase CK2 (casein kinase II)

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