(Q44138146)

30 November 2017

title

The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer (English)

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30 November 2017

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Annemarie H van Hattum

1

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30 November 2017

Herbert M Pinedo

2

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30 November 2017

Hennie M M Schlüper

3

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30 November 2017

Caroline A M Erkelens

4

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30 November 2017

Akiko Tohgo

5

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30 November 2017

Epie Boven

6

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30 November 2017

language of work or name

English

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publication date

1 October 2002

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30 November 2017

published in

Biochemical Pharmacology

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30 November 2017

volume

64

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30 November 2017

issue

8

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30 November 2017

page(s)

1267-1277

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A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo.

30 November 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Potent and broad antitumor effects of DX-8951f, a water-soluble camptothecin derivative, against various human tumors xenografted in nude mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Clinical applications of the camptothecins.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Antitumor effect of DX-8951, a novel camptothecin analog, on human pancreatic tumor cells and their CPT-11-resistant variants cultured in vitro and xenografted into nude mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Structural, mechanistic and clinical aspects of MRP1.

7 January 2021

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Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Major vault protein LRP-related multidrug resistance

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Clinical pharmacokinetics of topotecan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Sequences of topotecan and cisplatin: phase I, pharmacologic, and in vitro studies to examine sequence dependence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

Human liver microsomal metabolism of paclitaxel and drug interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901297-2

10.1016/S0006-2952(02)01297-2

7 January 2021

Identifiers

DOI

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30 November 2017

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