(Q44150756)

30 November 2017

title

Stereoselectivity of ibuprofen metabolism and pharmacokinetics following the administration of the racemate to healthy volunteers (English)

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30 November 2017

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Tan SC

1

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30 November 2017

Patel BK

2

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30 November 2017

Jackson SH

3

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30 November 2017

Swift CG

4

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30 November 2017

Hutt AJ

5

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30 November 2017

language of work or name

English

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publication date

1 August 2002

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30 November 2017

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30 November 2017

volume

32

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30 November 2017

issue

8

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30 November 2017

page(s)

683-697

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Some biological properties of 2-(4-isobutylphenyl)-propionic acid

30 November 2017

cites work

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https://api.crossref.org/works/10.1080%2F00498250210142994

Clinical pharmacokinetics of ibuprofen. The first 30 years

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Lack of effect of cimetidine on the pharmacokinetics of R(-)- and S(+)-ibuprofen

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250210142994

Stereoselective plasma protein binding of ibuprofen enantiomers

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250210142994

Variability in the stereoselective disposition of ibuprofen in patients with rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250210142994

The metabolic chiral inversion of 2-arylpropionic acids—a novel route with pharmacological consequences

21 January 2018

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Isomeric inversion of ibuprofen (R)-enantiomer in humans

21 January 2018

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Lack of effect of gender and oral contraceptive steroids on the pharmacokinetics of (R)-ibuprofen in humans

21 January 2018

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Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs--1. In vitro studies of ibuprofen and flurbiprofen

21 January 2018

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A 13C NMR study on ibuprofen metabolism in isolated rat liver mitochondria.

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250210142994

Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs—II Racemization and hydrolysis of (R)- and (S)-ibuprofen-CoA thioesters

21 January 2018

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The stereoselective uptake of ibuprofen enantiomers into adipose tissue

21 January 2018

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Interindividual variability in the enantiomeric disposition of ibuprofen following the oral administration of the racemic drug to healthy volunteers

21 January 2018

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https://api.crossref.org/works/10.1080%2F00498250210142994

Separation of the enantiomers of ibuprofen and its major phase I metabolites in urine using capillary electrophoresis

21 January 2018

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The relationship between the pharmacokinetics of ibuprofen enantiomers and the dose of racemic ibuprofen in humans

21 January 2018

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Chiral capillary electrophoresis–electrospray mass spectrometry coupling using vancomycin as chiral selector

21 January 2018

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Pharmacokinetics of S(+)- and R(-)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis.

21 January 2018

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Lack of presystemic inversion of (R)- to (S)-ibuprofen in humans

21 January 2018

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Errors in estimating the unbound fraction of drugs due to the volume shift in equilibrium dialysis

21 January 2018

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Isolation and characterization of major phase I and II metabolites of ibuprofen

21 January 2018

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Evidence of multiple forms of rat liver microsomal coenzyme A ligase catalysing the formation of 2-arylpropionyl-coenzyme A thioesters

21 January 2018

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Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations

21 January 2018

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Pharmacokinetics of ibuprofen in man. I. Free and total area/dose relationships

21 January 2018

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High-performance liquid chromatographic determination of the stereoisomeric metabolites of ibuprofen

21 January 2018

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Variability in the disposition of ibuprofen enantiomers in osteoarthritis patients

21 January 2018

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Effect of clofibrate on the chiral inversion of ibuprofen in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250210142994

Synthesis, chromatographic resolution and chiroptical properties of carboxyibuprofen stereoisomers: major metabolites of ibuprofen in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250210142994

Enzymatic inversion at saturated carbon: nature and mechanism of the inversion of R(-) p-iso-butyl hydratropic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250210142994

10.1080/00498250210142994

21 January 2018

Identifiers

DOI

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30 November 2017

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