(Q44158321)

30 November 2017

Dynamics and binding modes of free cdk2 and its two complexes with inhibitors studied by computer simulations (English)

1 reference

30 November 2017

1 reference

1

Michal Otyepka

1 reference

30 November 2017

3

Jaroslav Koca

1 reference

30 November 2017

Zdenek Kríz

2

1 reference

30 November 2017

1 October 2002

1 reference

Journal of Biomolecular Structure and Dynamics

30 November 2017

1 reference

30 November 2017

20

1 reference

30 November 2017

2

1 reference

30 November 2017

141-154

1 reference

Cyclin-dependent kinases: engines, clocks, and microprocessors

30 November 2017

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Protein kinase regulation: insights from crystal structure analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Structural basis for control by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Inhibition of cyclin-dependent kinases by purine analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Characterization of novel inhibitors of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Small-molecule inhibitors of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Crystal structure of cyclin-dependent kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Chemical inhibitors of cyclin-dependent kinases: insights into design from X-ray crystallographic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

The dynamics of cyclin dependent kinase structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Structural basis of cyclin-dependent kinase activation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

WHAT IF: a molecular modeling and drug design program

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Grand canonical ensemble Monte Carlo simulation of the dCpG/proflavine crystal hydrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Use of MM-PBSA in reproducing the binding free energies to HIV-1 RT of TIBO derivatives and predicting the binding mode to HIV-1 RT of efavirenz by docking and MM-PBSA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Docking-Based Development of Purine-like Inhibitors of Cyclin-Dependent Kinase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Crystal structure of human cyclin-dependent kinase 2 in complex with the adenine-derived inhibitor H717

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2002.10506830

10.1080/07391102.2002.10506830

21 January 2018

Identifiers

DOI

1 reference

30 November 2017

1 reference

PubMed ID

12354066