(Q44160494)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

A yeast-based in vivo bioassay to screen for class I phosphatidylinositol 3-kinase specific inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

Isabel Rodríguez-Escudero

5 February 2020

author

2

1 reference

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5 February 2020

José R Tormo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Teresa Fernández-Acero

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

Francisca Vicente

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Maria Cândida Monteiro

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Juan Cantizani

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

María Molina

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Víctor J Cid

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

publication date

15 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

5 February 2020

published in

1 reference

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5 February 2020

volume

17

1 reference

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5 February 2020

issue

8

1 reference

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5 February 2020

page(s)

1018-1029

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706348%20AND%20SRC:MED&resulttype=core&format=json

The PI3K pathway as drug target in human cancer

5 February 2020

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21 January 2018

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Phosphatidylinositol 3-kinase-dependent activation of mammalian protein kinase B/Akt in Saccharomyces cerevisiae, an in vivo model for the functional study of Akt mutations

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Inhibition of Cdc42-dependent signalling in Saccharomyces cerevisiae by phosphatase-dead SigD/SopB from Salmonella typhimurium

21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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Integration of multiple readouts into the z' factor for assay quality assessment

21 January 2018

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Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors

21 January 2018

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Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha

21 January 2018

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From genetics and genomics to drug discovery: yeast rises to the challenge

21 January 2018

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A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

21 January 2018

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Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor

21 January 2018

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The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

21 January 2018

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21 January 2018

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Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts

21 January 2018

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A robust screen for inhibitors and enhancers of phosphoinositide-3 kinase (PI3K) activities by ratiometric fluorescence superquenching

21 January 2018

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Automated high content screening for phosphoinositide 3 kinase inhibition using an AKT 1 redistribution assay.

21 January 2018

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A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo

21 January 2018

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Antisense-guided isolation and structure elucidation of pannomycin, a substituted cis-decalin from Geomyces pannorum

21 January 2018

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