(Q37270429)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

review article

1 reference

title

Assessment of PTEN tumor suppressor activity in nonmammalian models: the year of the yeast (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

Isabel Rodríguez-Escudero

14 January 2020

author

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Amparo Andrés-Pons

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Carlos Romá-Mateo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Rafael Pulido

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

V J Cid

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

A Gil

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

J den Hertog

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

M Molina

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

English

0 references

publication date

1 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

5431-5442

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

Disruption of a single Pten allele augments the chemotactic response of B lymphocytes to stromal cell-derived factor-1.

14 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

1 reference

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PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Targeting phosphoinositide 3-kinase: moving towards therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Control of stress-regulated gene expression and longevity by the Sch9 protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Alternative splicing of the human PTEN/MMAC1/TEP1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Alternative splicing of the Drosophila PTEN gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

In vivo functional analysis of the counterbalance of hyperactive phosphatidylinositol 3-kinase p110 catalytic oncoproteins by the tumor suppressor PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

31 March 2020

The two TORCs and Akt.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN function in normal and neoplastic growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Ptena and ptenb genes play distinct roles in zebrafish embryogenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of longevity and stress resistance by Sch9 in yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

A tumor suppressor homolog, AtPTEN1, is essential for pollen development in Arabidopsis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Chemotaxis in the Absence of PIP3 Gradients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Screening patients for heterozygous p53 mutations using a functional assay in yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Mutation of the PIK3CA oncogene in human cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Physiological functions of Pten in mouse tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN regulates motility but not directionality during leukocyte chemotaxis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN and myotubularin: novel phosphoinositide phosphatases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Yeast as a model for medical and medicinal research

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

From genetics and genomics to drug discovery: yeast rises to the challenge

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of chronological aging in Schizosaccharomyces pombe by the protein kinases Pka1 and Sck2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Regulation of the activity of the tumor suppressor PTEN by thioredoxin in Drosophila melanogaster

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Portrait of PTEN: messages from mutant mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Detection of APC mutations by a yeast-based protein truncation test (YPTT).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

31 March 2020

New insights into PTEN.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

A streamlined process to phenotypically profile heterologous cDNAs in parallel using yeast cell-based assays

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN is required for the normal progression of gastrulation by repressing cell proliferation after MBT in Xenopus embryos.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Cancer-specific mutations in phosphatidylinositol 3-kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Pkh-kinases control eisosome assembly and organization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Investigate the role of PTEN in chemotaxis of human breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.240

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794878%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference