(Q44163138)

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1-Methyl-4-phenylpridinium (MPP+)-induced functional run-down of GABA(A) receptor-mediated currents in acutely dissociated dopaminergic neurons.

scientific article published in October 2002

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12358732%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

1-Methyl-4-phenylpridinium (MPP+)-induced functional run-down of GABA(A) receptor-mediated currents in acutely dissociated dopaminergic neurons (English)

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Europe PubMed Central

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13 December 2019

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Linda Partridge

5

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13 December 2019

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Jie Wu

1

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13 December 2019

Piu Chan

2

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13 December 2019

Katherine M Schroeder

3

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13 December 2019

Kevin Ellsworth

4

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13 December 2019

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1 October 2002

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13 December 2019

Journal of Neurochemistry

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13 December 2019

83

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13 December 2019

1

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13 December 2019

87-99

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13 December 2019

Involvement of phosphatase activities in the run-down of GABA(A) receptor function in rat cerebellar granule cells in culture

1 reference

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Repeated administration of N-methyl-4-phenyl 1,2,5,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones

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1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway

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Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain

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GABAA receptor function is regulated by phosphorylation in acutely dissociated guinea-pig hippocampal neurones.

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Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

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Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes

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A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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The GABAergic striatonigral neurons of the cat: demonstration by double peroxidase labeling

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Run-down of the GABAA response under experimental ischaemia in acutely dissociated CA1 pyramidal neurones of the rat.

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21 January 2018

Identification of a subpopulation of substantia nigra pars compacta gamma-aminobutyric acid neurons that is regulated by basal ganglia activity

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Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity

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21 January 2018

Muscarinic activation of ionic currents measured by a new whole-cell recording method

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21 January 2018

Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?

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21 January 2018

Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP.

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21 January 2018

Neuroprotective therapy for Parkinson's disease

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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra

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Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

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Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

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Distribution of high affinity sodium-independent [3H]gamma-aminobutyric acid [3H]GABA binding in the human brain: alterations in Parkinson's disease

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GABAA receptor channels

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Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

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Excitatory amino acid neurotoxicity and neurodegenerative disease

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MPP+ (1-methyl-4-phenylpyridine) is a neurotoxin to dopamine-, norepinephrine- and serotonin-containing neurons

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Taurine-induced attenuation of MPP+ neurotoxicity in vitro: a possible role for the GABA(A) subclass of GABA receptors

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Drug interactions at the GABA receptor-ionophore complex

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Immunocytochemical localization of glutamate decarboxylase in rat substantia nigra

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GABA receptor binding in the parkinsonian brain

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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on ATP levels of mouse brain synaptosomes.

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Experimental hemiparkinsonism in the rat following chronic unilateral infusion of MPP+ into the nigrostriatal dopamine pathway--I. Behavioural, neurochemical and histological characterization of the lesion

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The output neurones and the dopaminergic neurones of the substantia nigra receive a GABA-containing input from the globus pallidus in the rat.

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GABAA-receptor function in hippocampal cells is maintained by phosphorylation factors

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Dissociated dopaminergic neurons from substantia nigra zona compacta in young rats lack functional NMDA receptors

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Sevoflurane-induced ionic current in acutely dissociated CA1 pyramidal neurons of the rat hippocampus

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Potentiation by sevoflurane of the gamma-aminobutyric acid-induced chloride current in acutely dissociated CA1 pyramidal neurones from rat hippocampus

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