(Q44163171)

30 November 2017

title

A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism (English)

1 reference

30 November 2017

1 reference

7

Ted M Dawson

1 reference

30 November 2017

Allen S Mandir

1

1 reference

30 November 2017

Cynthia M Simbulan-Rosenthal

2

1 reference

30 November 2017

Marc F Poitras

3

1 reference

30 November 2017

John R Lumpkin

4

1 reference

30 November 2017

Valina L Dawson

5

1 reference

30 November 2017

Mark E Smulson

6

1 reference

30 November 2017

language of work or name

English

0 references

publication date

1 October 2002

1 reference

Journal of Neurochemistry

30 November 2017

number of pages

7

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

30 November 2017

volume

83

1 reference

30 November 2017

issue

1

1 reference

30 November 2017

page(s)

186-192

1 reference

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

30 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Loss of function and p53 protein stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Increase in bax expression in substantia nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Bright and dark sides of nitric oxide in ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Role of reactive oxygen species in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Regulation and activation of p53 and its family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Nitric oxide synthase inhibition and MPTP-induced toxicity in the common marmoset

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Mechanisms of switching on p53: a role for covalent modification?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

MDM2--master regulator of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

7-Nitroindazole prevents 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced ATP loss in the mouse striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Neurochemical findings in the MPTP model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Poly(ADP-ribose) glycohydrolase is present and active in mammalian cells as a 110-kDa protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Cell death and apoptosis regulating proteins in Parkinson's disease--a cautionary note

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

10.1046/J.1471-4159.2002.01144.X

21 January 2018

Identifiers

DOI

1 reference

30 November 2017

1 reference