(Q44184704)

English

Abeta[25-35] peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2O2, caspase-3, NF-kappaB, p53 and c-Jun.

scientific article published in September 2002

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14 December 2019

Abeta[25-35] peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2O2, caspase-3, NF-kappaB, p53 and c-Jun (English)

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14 December 2019

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Carlos Velez-Pardo

1

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14 December 2019

author name string

Gloria Garcia Ospina

2

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14 December 2019

Marlene Jimenez del Rio

3

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1 September 2002

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14 December 2019

NeuroToxicology

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14 December 2019

23

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14 December 2019

3

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14 December 2019

351-365

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14 December 2019

Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.

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Activate NF-kappa B or die?

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beta-amyloid peptides are cytotoxic to astrocytes in culture: a role for oxidative stress.

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Regulation of gene expression by reactive oxygen

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Activation of caspase 3 in HL-60 cells exposed to hydrogen peroxide

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c-Jun promotes neurite outgrowth and survival in PC12 cells

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Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

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Lymphocytes and neutrophils as peripheral models to study the effect of beta-amyloid on cellular calcium signalling in Alzheimer's disease

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Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered.

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7 January 2021

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Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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MEKK1/JNK signaling stabilizes and activates p53.

1 reference

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7 January 2021

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Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

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7 January 2021

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p53 and apoptosis

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7 January 2021

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Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent

1 reference

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Selective interaction of JNK protein kinase isoforms with transcription factors

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

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Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons.

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Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

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The biochemistry of apoptosis

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A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

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The c-Jun transcription factor--bipotential mediator of neuronal death, survival and regeneration

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17 beta-estradiol protects lymphocytes against dopamine and iron-induced apoptosis by a genomic-independent mechanism. Implication in Parkinson's disease

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1 reference

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The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus

1 reference

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Transforming growth factor-beta inhibits apoptosis induced by beta-amyloid peptide fragment 25-35 in cultured neuronal cells

1 reference

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1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

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7 January 2021

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1 reference

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7 January 2021

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Beta-amyloid-induced activation of caspase-3 in primary cultures of rat neurons

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation.

1 reference

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1 reference

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1 reference

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7 January 2021

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Oxidative damage to DNA in lymphocytes from AD patients.

1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The central effectors of cell death in the immune system

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Flow cytometric assays of oxidative burst activity in phagocytes

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid peptides are toxic via a common oxidative mechanism

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900081-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900081-5

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of AP-1 and Nuclear Factor-κB Transcription Factors Is Involved in Hydrogen Peroxide-Induced Apoptotic Cell Death of Olligodendrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900081-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrogen peroxide-induced oxidative damage and apoptosis in cerebellar granule cells: protection by Ginkgo biloba extract

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900081-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Toxicity of iron and hydrogen peroxide: the Fenton reaction

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid beta-mediated oxidative and metabolic stress in rat cortical neurons: no direct evidence for a role for H2O2 generation.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0161-813X(02)00081-5

1 reference

Europe PubMed Central

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14 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12387362%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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