(Q44187571)

English

Activation of AMP-activated protein kinase and phosphorylation of glycogen synthase kinase3 β mediate ursolic acid induced apoptosis in HepG2 liver cancer cells

scientific article published on 16 January 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Activation of AMP-activated protein kinase and phosphorylation of glycogen synthase kinase3 β mediate ursolic acid induced apoptosis in HepG2 liver cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

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author name string

Hyun-Soo Son

1

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Hee Young Kwon

2

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Eun Jung Sohn

3

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Jang-Hoon Lee

4

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Hong-Jung Woo

5

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Miyong Yun

6

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Sung-Hoon Kim

7

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Young-Chul Kim

8

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PubMed publication ID

30 November 2017

language of work or name

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publication date

16 January 2013

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Europe PubMed Central

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30 November 2017

Phytotherapy Research

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Europe PubMed Central

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30 November 2017

27

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Europe PubMed Central

PubMed publication ID

30 November 2017

11

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Europe PubMed Central

PubMed publication ID

30 November 2017

1714-1722

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Europe PubMed Central

PubMed publication ID

30 November 2017

Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace

1 reference

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21 January 2018

Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines

1 reference

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21 January 2018

Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism.

1 reference

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21 January 2018

Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression.

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21 January 2018

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

1 reference

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21 January 2018

Therapeutic strategies within the ubiquitin proteasome system.

1 reference

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21 January 2018

AMPK: a key regulator of energy balance in the single cell and the whole organism.

1 reference

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21 January 2018

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action

1 reference

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21 January 2018

The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells

1 reference

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21 January 2018

Herbal extract "Songyou Yin" inhibits tumor growth and prolongs survival in nude mice bearing human hepatocellular carcinoma xenograft with high metastatic potential

1 reference

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21 January 2018

Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways

1 reference

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21 January 2018

Ursolic acid: an anti- and pro-inflammatory triterpenoid

1 reference

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21 January 2018

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

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21 January 2018

Antidiabetic effect of propolis: reduction of expression of glucose‐6‐phosphatase through inhibition of Y279 and Y216 autophosphorylation of GSK‐3α/β in HepG2 cells

1 reference

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21 January 2018

AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase

1 reference

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21 January 2018

A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway

1 reference

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21 January 2018

Glycogen synthase kinase-3--an overview of an over-achieving protein kinase

1 reference

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21 January 2018

GSK-3 in Neurodegenerative Diseases.

1 reference

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21 January 2018

Herbal medicine and hepatocellular carcinoma: applications and challenges

1 reference

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21 January 2018

Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Re-evaluating the general(ized) roles of AMPK in cellular metabolism

1 reference

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21 January 2018

Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells

1 reference

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21 January 2018

Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells.

1 reference

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21 January 2018

Inhibition of GSK3 by Wnt signalling--two contrasting models

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Ursolic acid from Oldenlandia diffusa induces apoptosis via activation of caspases and phosphorylation of glycogen synthase kinase 3 beta in SK-OV-3 ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Prodigiosin induces the proapoptotic gene NAG-1 via glycogen synthase kinase-3beta activity in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Inhibition of the ubiquitin-proteasome system by natural products for cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3beta constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

1 reference

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21 January 2018

Second-line therapies in hepatocellular carcinoma: emergence of resistance to sorafenib

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Effects of ursolic acid on the proliferation and apoptosis of human ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor

1 reference

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21 January 2018

Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

1 reference

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21 January 2018

Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4925

21 January 2018

Identifiers

10.1002/PTR.4925

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

ResearchGate publication ID

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