(Q44195095)

English

Modulation of the electrophoretic mobility of the linker for activation of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a potential substrate for PKC and calcineurin signaling pathways.

scientific article published in January 2003

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14 December 2019

Modulation of the electrophoretic mobility of the linker for activation of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a potential substrate for PKC and calcineurin signaling pathways (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12401523%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Johny E Elkahwaji

2

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14 December 2019

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Clifford S Cho

1

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14 December 2019

Zheng Chang

3

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14 December 2019

Tara L Scheunemann

4

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14 December 2019

Eric R Manthei

5

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14 December 2019

Majed M Hamawy

6

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14 December 2019

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1 January 2003

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14 December 2019

Cellular Signalling

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14 December 2019

15

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14 December 2019

1

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14 December 2019

85-93

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14 December 2019

Regulation of antigen receptor signal transduction by protein tyrosine kinases

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Signal transduction by the TCR for antigen

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7 January 2021

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T cell antigen-receptor signal transduction

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Phosphatases and kinases in lymphocyte signaling

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Tumor chemoconversion following surgery, chemotherapy, and normalization of serum tumor markers in a woman with a mixed type germ cell ovarian tumor

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The transmembrane adapter LAT plays a central role in immune receptor signalling.

1 reference

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Vav proteins, adaptors and cell signaling.

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The role of the adapter molecule SLP-76 in platelet function

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Immunosuppressive strategies in transplantation

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Immunosuppressants: cellular and molecular mechanisms of action

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New immunosuppressive agents for maintenance therapy in organ transplantation

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7 January 2021

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900046-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

1 reference

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7 January 2021

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inferred from DOI database lookup

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

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7 January 2021

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The calcium/calmodulin-dependent protein phosphatase calcineurin is the major Elk-1 phosphatase

1 reference

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7 January 2021

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Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

1 reference

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7 January 2021

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Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

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7 January 2021

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

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7 January 2021

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Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions

1 reference

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7 January 2021

based on heuristic

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CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900046-3

7 January 2021

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Identification of the minimal tyrosine residues required for linker for activation of T cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900046-3

7 January 2021

based on heuristic

inferred from DOI database lookup

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

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7 January 2021

based on heuristic

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Essential role of LAT in T cell development

1 reference

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7 January 2021

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Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

1 reference

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7 January 2021

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Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900046-3

7 January 2021

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Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900046-3

7 January 2021

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inferred from DOI database lookup

CD28 ligation induces tyrosine phosphorylation of Pyk2 but not Fak in Jurkat T cells

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Immunopharmacology of rapamycin

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Cantharidin-binding protein: identification as protein phosphatase 2A

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Protein phosphatase inhibitor okadaic acid enhances transmitter release at neuromuscular junctions

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Okadaic acid: a new probe for the study of cellular regulation

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Calyculin A and okadaic acid: inhibitors of protein phosphatase activity

1 reference

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based on heuristic

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Calyculin A, a potent inhibitor of phosphatases-1 and -2A, prevents apoptosis

1 reference

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based on heuristic

inferred from DOI database lookup

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

1 reference

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based on heuristic

inferred from DOI database lookup

Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons.

1 reference

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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

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inferred from DOI database lookup

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

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Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation

1 reference

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FK506 and Cyclosporin A Each Inhibit Antigen-Specific Signaling in the T Cell Line 171 in the Absence of a Calcium Signal

1 reference

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inferred from DOI database lookup

Stimulation of transforming growth factor-beta 1 transcription by cyclosporine

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Transforming growth factor (TGF)-beta mimics and anti-TGF-beta antibody abrogates the in vivo effects of cyclosporine: demonstration of a direct role of TGF-beta in immunosuppression and nephrotoxicity of cyclosporine

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Identifiers

10.1016/S0898-6568(02)00046-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12401523%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12401523%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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