(Q44198855)

30 November 2017

Persistent hepatic expression of human apo A-I after transfer with a helper-virus independent adenoviral vector (English)

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30 November 2017

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Van Linthout S

1

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30 November 2017

Lusky M

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2

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30 November 2017

Collen D

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3

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30 November 2017

De Geest B

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4

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30 November 2017

1 November 2002

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30 November 2017

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30 November 2017

9

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30 November 2017

22

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30 November 2017

1520-1528

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301824

30 November 2017

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cites work

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

High-capacity adenoviral vectors for gene transfer and somatic gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Persistent transgene expression in mouse liver following in vivo gene transfer with a delta E1/delta E4 adenovirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Dystrophin expression in muscle following gene transfer with a fully deleted ("gutted") adenovirus is markedly improved by trans-acting adenoviral gene products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Sustained expression of human apo A-I following adenoviral gene transfer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Heterologous expression of adenovirus E3-gp19K in an E1a-deleted adenovirus vector inhibits MHC I expression in vitro, but does not prolong transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Overcoming cellular immunity to prolong adenoviral-mediated gene expression in sciatic nerve.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Local high-capacity adenovirus-mediated mCTLA4Ig and mCD40Ig expression prolongs recombinant gene expression in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Two adenovirus proteins with redundant activities in virus growth facilitates tripartite leader mRNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Effects of adenovirus-mediated human apo A-I gene transfer on neointima formation after endothelial denudation in apo E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Generation of an adenovirus vector lacking E1, e2a, E3, and all of E4 except open reading frame 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Effect of the E4 region on the persistence of transgene expression from adenovirus vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

E4ORF3 requirement for achieving long-term transgene expression from the cytomegalovirus promoter in adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Effect of promoters and enhancers on expression, transgene DNA persistence, and hepatotoxicity after adenoviral gene transfer of human apolipoprotein A-I

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Adenovirus vector-infected cells can escape adenovirus antigen-specific cytotoxic T-lymphocyte killing in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Properties of intracellular bovine papillomavirus chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Sustained expression of human apolipoprotein A-I after adenoviral gene transfer in C57BL/6 mice: role of apolipoprotein A-I promoter, apolipoprotein A-I introns, and human apolipoprotein E enhancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301824

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301824

1 reference

30 November 2017

1 reference