(Q44203191)

English

Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity

scientific article published in December 2002

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

30 November 2017

Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity (English)

1 reference

Europe PubMed Central

30 November 2017

Ewa Chojnacka-Wójcik

8

object named as

Ewa Chojnacka-Wójcik

1 reference

Europe PubMed Central

30 November 2017

Ewa Tatarczyńska

6

object named as

Ewa Tatarczyńska

1 reference

Europe PubMed Central

30 November 2017

Beata Duszyńska

4

object named as

Beata Duszyńska

1 reference

Europe PubMed Central

30 November 2017

Aleksandra Kłodzińska

7

object named as

Aleksandra Kłodzińska

1 reference

Europe PubMed Central

30 November 2017

Andrzej Bojarski

1

object named as

Andrzej J Bojarski

1 reference

Europe PubMed Central

30 November 2017

author name string

Piotr Kowalski

2

1 reference

Europe PubMed Central

30 November 2017

Teresa Kowalska

3

1 reference

Europe PubMed Central

30 November 2017

Sijka Charakchieva-Minol

5

1 reference

Europe PubMed Central

30 November 2017

language of work or name

0 references

publication date

1 December 2002

1 reference

Europe PubMed Central

30 November 2017

Bioorganic & Medicinal Chemistry

1 reference

Europe PubMed Central

30 November 2017

10

1 reference

Europe PubMed Central

30 November 2017

12

1 reference

Europe PubMed Central

30 November 2017

3817-3827

1 reference

Europe PubMed Central

30 November 2017

Structure-activity relationship studies of CNS agents. Part 38. Novel 1,4-benzoxazin-3(4H)-one, 1,2-benzoxazolin-3-one and 1,3-benzoxazolin-2,4-dione arylpiperazine derivatives with different 5-HT1A and antagonistic 5-HT2A activities

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4()-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The Reactions of Maleic Anhydride with Hydrazine Hydrate1

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

An ethopharmacological analysis of the behavioral effects of 8-OH-DPAT.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective activation of 5HT1A receptors induces lower lip retraction in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamino)tetralin in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Do functional relationships exist between 5-HT1A and 5-HT2 receptors?

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A simple and reliable conflict procedure for testing anti-anxiety agents

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone. IV. Influence of haloperidol (R 1625) and of chlorpromazine on the behaviour of rats in an unfamiliar "open field" situation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

5-HT1A receptor agonists: recent developments and controversial issues

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN-190.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of 5-HT1A receptor agonists, partial agonists and a silent antagonist on the performance of the conditioned emotional response test in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

5HT2 receptors, depression and anxiety

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Opposite effects of nefazodone in two human models of anxiety

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The novel buspirone analogue, 8-[4-[2-(1,2,3,4-tetrahydroisoquinolinyl)[butyl]-8-azaspiro [4.5 ]decane-7,9-dione, with anxiolytic-like and antidepressant-like effects in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective agonists and antagonists for 5-hydroxytryptamine receptor subtypes, and interactions with yohimbine and FG 7142 using the elevated plus-maze test in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects in the X-maze anxiety model of agents acting at 5-HT1 and 5-HT2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Ipsapirone depresses neuronal activity in the dorsal raphe nucleus and the hippocampal formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Antidepressant-like activity of ipsapirone, buspirone and gepirone in the forced swimming test in rats pretreated with proadifen

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Different effects of intracerebral and systemic administration of buspirone in the forced swimming test: involvement of a metabolite.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain monoamine receptors in a chronic unpredictable stress model in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900349-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0968-0896(02)00349-8

1 reference

Europe PubMed Central

30 November 2017

1 reference

Europe PubMed Central

30 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44203191&oldid=2152947888"