(Q44225345)

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Selective changes in the levels of nicotinic acetylcholine receptor protein and of corresponding mRNA species in the brains of patients with Parkinson's disease.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Selective changes in the levels of nicotinic acetylcholine receptor protein and of corresponding mRNA species in the brains of patients with Parkinson's disease (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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Zhi-Zhong Guan

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Malahat Mousavi

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Ewa Hellström-Lindahl

5

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15 December 2019

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1 November 2002

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15 December 2019

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

956

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15 December 2019

2

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15 December 2019

358-366

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15 December 2019

Schizophrenia, sensory gating, and nicotinic receptors

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Cellular expression of alpha7 nicotinic acetylcholine receptor protein in the temporal cortex in Alzheimer's and Parkinson's disease--a stereological approach

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Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients.

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Nicotine binding in human striatum: elevation in schizophrenia and reductions in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease and in relation to neuroleptic medication.

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A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

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Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

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Human post-mortem striatal alpha4beta2 nicotinic acetylcholine receptor density in schizophrenia and Parkinson's syndrome

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6-hydroxydopamine lesion of rat nigrostriatal dopaminergic neurons differentially affects nicotinic acetylcholine receptor subunit mRNA expression.

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Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

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Human neuronal nicotinic receptors

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Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain

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Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease

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Regional distribution of nicotinic receptor subunit mRNAs in human brain: comparison between Alzheimer and normal brain

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Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases

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Nicotinic receptors in the brain: correlating physiology with function

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Differential inhibition by alpha-conotoxin-MII of the nicotinic stimulation of [3H]dopamine release from rat striatal synaptosomes and slices.

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Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors

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7 January 2021

Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes.

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Role of dopamine in learning and memory: implications for the treatment of cognitive dysfunction in patients with Parkinson's disease

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Altered muscarinic and nicotinic receptor densities in cortical and subcortical brain regions in Parkinson's disease

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Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion

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alpha7 nicotinic receptor-mediated protection against ethanol-induced oxidative stress and cytotoxicity in PC12 cells

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Nicotinic acetylcholine receptors in health and disease

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Parkinson's disease

1 reference

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Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease

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7 January 2021

Alpha and beta nicotinic acetylcholine receptors subunits and synaptophysin in putamen from Parkinson's disease

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Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia.

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Alpha-synuclein-immunoreactive cortical Lewy bodies are associated with cognitive impairment in Parkinson's disease.

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3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner

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Neurochemical and neurogenetic correlates of Parkinson's disease.

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Nicotinic systems in central nervous systems disease: degenerative disorders and beyond

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Human nicotinic receptors--their role in aging and dementia

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Neuronal nicotinic receptors in the human brain

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Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease.

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Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology

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Nicotinic receptor abnormalities in Alzheimer's and Parkinson's diseases

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Identifiers

10.1016/S0006-8993(02)03571-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12445706%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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