(Q44237367)

1 December 2017

title

Identification of novel enzyme-prodrug combinations for use in cytochrome P450-based gene therapy for cancer (English)

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1 December 2017

4

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1 December 2017

Alex Baldwin

1

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1 December 2017

Zeqi Huang

series ordinal

2

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1 December 2017

Youssef Jounaidi

series ordinal

3

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1 December 2017

language of work or name

English

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publication date

1 January 2003

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Archives of Biochemistry and Biophysics

1 December 2017

published in

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1 December 2017

volume

409

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1 December 2017

issue

1

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1 December 2017

page(s)

197-206

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Hepatic microsomes and drug oxidation

1 December 2017

cites work

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Metabolism and pharmacokinetics of oxazaphosphorines

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Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene

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Cytochrome P450-based cancer gene therapy: recent advances and future prospects

7 January 2021

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Cytochrome P450 gene-directed enzyme prodrug therapy (GDEPT) for cancer

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Cancer gene therapy: scientific basis.

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The role of the bystander effect in suicide gene therapy

7 January 2021

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Gene therapy against cancer and HIV infection using the gene encoding herpes simplex virus thymidine kinase.

7 January 2021

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In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping study.

7 January 2021

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Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s

7 January 2021

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Differential single- versus double-strand DNA breakage produced by doxorubicin and its morpholinyl analogues

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Metabolic conversion of methoxymorpholinyl doxorubicin: from a DNA strand breaker to a DNA cross-linker

7 January 2021

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Broad phase II and pharmacokinetic study of methoxy-morpholino doxorubicin (FCE 23762-MMRDX) in non-small-cell lung cancer, renal cancer and other solid tumour patients

7 January 2021

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A rapid in vitro method for the evaluation of potential antitumor drugs requiring metabolic activation by hepatic S9 enzymes

7 January 2021

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Morphological studies of rat brain tumors induced by N-nitrosomethylurea

7 January 2021

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Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes

7 January 2021

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Expression and inducibility of cytochrome P450 3A9 (CYP3A9) and other members of the CYP3A subfamily in rat liver

7 January 2021

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Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.

7 January 2021

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Cytochrome P450 metabolic intermediate complexes from macrolide antibiotics and related compounds

7 January 2021

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7 January 2021

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The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions

7 January 2021

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Interaction of anticancer drugs with hepatic monooxygenase enzymes

7 January 2021

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Phenobarbital induction of cytochrome P-450 gene expression

7 January 2021

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Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

7 January 2021

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Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

7 January 2021

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Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists

7 January 2021

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Interaction with type II estrogen binding sites and antiproliferative activity of tamoxifen and quercetin in human non-small-cell lung cancer

7 January 2021

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Effect of tamoxifen, a nonsteroidal antiestrogen, on phospholipid/calcium-dependent protein kinase and phosphorylation of its endogenous substrate proteins from the rat brain and ovary.

7 January 2021

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Tamoxifen metabolism by microsomal cytochrome P450 and flavin-containing monooxygenase

7 January 2021

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10.1016/S0003-9861(02)00453-8

7 January 2021

Identifiers

DOI

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1 December 2017

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