(Q44259003)

1 December 2017

title

Identification of gene-selective modulators of the bile acid receptor FXR. (English)

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1 December 2017

Isabelle Dussault

1

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1 December 2017

Rick Beard

2

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1 December 2017

Min Lin

3

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1 December 2017

Kevin Hollister

4

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1 December 2017

Jasmine Chen

5

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1 December 2017

Jia-Hao Xiao

6

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1 December 2017

Rosh Chandraratna

7

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1 December 2017

Barry M Forman

8

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1 December 2017

language of work or name

English

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publication date

19 December 2002

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Journal of Biological Chemistry

1 December 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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1 December 2017

volume

278

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1 December 2017

issue

9

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1 December 2017

page(s)

7027-7033

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 December 2017

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Molecular link between cholesterol, cytokines and atherosclerosis

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New National Cholesterol Education Program III guidelines for primary prevention lipid-lowering drug therapy: projected impact on the size, sex, and age distribution of the treatment-eligible population

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Regulation of bile acid synthesis

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Nuclear orphan receptors control cholesterol catabolism.

21 January 2018

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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Identification of a nuclear receptor for bile acids

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Bile acids: natural ligands for an orphan nuclear receptor

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

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The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

21 January 2018

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Inhibition of Estrogen Receptor Action by the Orphan Receptor SHP (Short Heterodimer Partner)

21 January 2018

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Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

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Identification of a nuclear receptor that is activated by farnesol metabolites

21 January 2018

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Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

21 January 2018

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A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

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Chenodeoxycholic acid: a review of its pharmacological properties and therapeutic use.

21 January 2018

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Identification of a chemical tool for the orphan nuclear receptor FXR.

21 January 2018

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Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

21 January 2018

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Determinants of target gene specificity for steroid/thyroid hormone receptors

21 January 2018

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SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

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Activation of the orphan receptor RIP14 by retinoids

21 January 2018

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Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids

21 January 2018

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Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma

21 January 2018

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Coregulator codes of transcriptional regulation by nuclear receptors

21 January 2018

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Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

21 January 2018

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Activation of specific RXR heterodimers by an antagonist of RXR homodimers

21 January 2018

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Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol

21 January 2018

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Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators

21 January 2018

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Quality control of receptor-kinase signaling complexes

21 January 2018

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The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor

21 January 2018

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A natural product that lowers cholesterol as an antagonist ligand for FXR.

21 January 2018

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An issue of tissues: divining the split personalities of selective estrogen receptor modulators

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M209863200

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1 December 2017

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