(Q44259205)

1 December 2017

Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents (English)

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1 December 2017

4

Jeffrey A Lieberman

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1 December 2017

Christine E Marx

1

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1 December 2017

Margaret J VanDoren

series ordinal

2

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1 December 2017

Gary E Duncan

series ordinal

3

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1 December 2017

A Leslie Morrow

series ordinal

5

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1 December 2017

language of work or name

English

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publication date

1 January 2003

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1 December 2017

Neuropsychopharmacology

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1 December 2017

28

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1 December 2017

1

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1 December 2017

1-13

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300015

1 December 2017

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cites work

Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Increased baseline occupancy of D2 receptors by dopamine in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Gender and the course of schizophrenia: differences in treated outcomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Radioreceptor binding profile of the atypical antipsychotic olanzapine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Glucocorticoids and progestins signal the initiation and enhance the rate of myelin formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Anxiolytic activity of an endogenous adrenal steroid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Dopamine in schizophrenia: a review and reconceptualization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The neurosteroid, 3 alpha-hydroxy-5 alpha-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Effects of acute metabolic stress on plasma progesterone and testosterone in male subjects: relationship to pituitary-adrenocortical axis activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Abstinent alcoholics exhibit an exaggerated stress response to 2-deoxy-D-glucose challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Clozapine in the treatment of refractory psychotic mania

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Regulation of the prefrontal cortical dopamine system by the neuroactive steroid 3a,21-dihydroxy-5a-pregnane-20-one

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Evidence for a role of neurosteroids in modulation of diurnal changes and acute stress-induced corticosterone secretion in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Effects of typical and atypical antipsychotic drugs on freezing behavior induced by conditioned fear

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Progesterone as a neurosteroid: synthesis and actions in rat glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

In Vivo Uptake of [3H]Progesterone and [3H]-5α-Dihydroprogesterone by Rat Brain and Pituitary and Effects of Estradiol and Time: Tissue Concentration of Progesterone Itself or Specific Metabolites?*

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one affects dopamine-mediated behavior in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one induces catalepsy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Olanzapine increases allopregnanolone in the rat cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Psychoneuroendocrinology of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Olanzapine in treatment-resistant bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Survey on the pharmacodynamics of the new antipsychotic risperidone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The blunted plasma cortisol response to apomorphine and its relationship to treatment response in patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Neuroactive steroid modulators of the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The neurosteroid tetrahydroprogesterone attenuates the endocrine response to stress and exerts glucocorticoid-like effects on vasopressin gene transcription in the rat hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Metabolic clearance rate of progesterone: comparison between ovariectomized, pregnant, pseudopregnant and deciduoma-bearing pseudopregnant rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Effects of antidepressant treatment on neuroactive steroids in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Psychopathology in women and men: focus on female hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

A novel augmentation strategy for treating resistant major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Fluoxetine decreases concentrations of 3 alpha, 5 alpha-tetrahydrodeoxycorticosterone (THDOC) in major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Gender differences in neuroleptic nonresponsive clozapine-treated schizophrenics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

A double-blind, controlled comparison of the novel antipsychotic olanzapine versus haloperidol or placebo on anxious and depressive symptoms accompanying schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. III. A new cohort and evidence for a monoaminergic mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

Effects of four antipsychotics on punished responding in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D1, D2, D3, 5HT2A and muscarinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

The effects of metabolic stress on plasma progesterone in healthy volunteers and schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Stimulation of progesterone release and estrous behavior by ACTH in ovariectomized rodents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Differential olanzapine plasma concentrations by sex in a fixed-dose study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Progesterone synthesis and myelin formation by Schwann cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Treatment of suicidality in schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Inhibition of basal and stress-induced dopamine release in the cerebral cortex and nucleus accumbens of freely moving rats by the neurosteroid allopregnanolone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Acute and long-term effectiveness of clozapine in treatment-resistant psychotic depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Long-term olanzapine therapy in the treatment of bipolar I disorder: an open-label continuation phase study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Current outcome in schizophrenia: women vs men

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Single-dose pharmacokinetics of fluphenazine after fluphenazine decanoate administration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Gender differences in onset of illness, treatment response, course, and biologic indexes in first-episode schizophrenic patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300015

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300015

1 reference

1 December 2017

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