(Q44269727)

1 July 2019

title

Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia (English)

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1 July 2019

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5

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author name string

Wen-Hsin Lu

1

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1 July 2019

Chih-Yen Wang

2

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1 July 2019

Po-See Chen

3

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1 July 2019

Jing-Wen Wang

4

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1 July 2019

Chung-Shi Yang

6

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1 July 2019

Shun-Fen Tzeng

7

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1 July 2019

publication date

13 February 2013

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1 July 2019

Journal of Neuroscience Research

published in

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1 July 2019

volume

91

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1 July 2019

issue

5

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1 July 2019

page(s)

694-705

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1 July 2019

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury.

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Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

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Regeneration of descending axon tracts after spinal cord injury

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Purinergic signalling in inflammation of the central nervous system

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Microglial phagocytosis attenuated by short-term exposure to exogenous ATP through P2X receptor action

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Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures.

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Inflammatory-mediated injury and repair in the traumatically injured spinal cord

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In vivo imaging of axonal degeneration and regeneration in the injured spinal cord

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Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action.

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Sodium butyrate suppresses interferon-gamma-, but not lipopolysaccharide-mediated induction of nitric oxide and tumor necrosis factor-alpha in microglia

21 January 2018

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Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

21 January 2018

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Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition

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Valproic acid improves locomotion in vivo after SCI and axonal growth of neurons in vitro

21 January 2018

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Repression of interferon-gamma-induced inducible nitric oxide synthase (iNOS) gene expression in microglia by sodium butyrate is mediated through specific inhibition of ERK signaling pathways

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Valproate reduces CHOP levels and preserves oligodendrocytes and axons after spinal cord injury.

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Purinoceptors in microglia and neuropathic pain

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P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

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Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

21 January 2018

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Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury

21 January 2018

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P2X7 receptor inhibition improves recovery after spinal cord injury

21 January 2018

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Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury

21 January 2018

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The role of p38 MAPK in valproic acid induced microglia apoptosis

21 January 2018

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The neuroprotective effect of treatment of valproic Acid in acute spinal cord injury

21 January 2018

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Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord

21 January 2018

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12 December 2020

A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: caspase-3 dependency

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12 December 2020

Temporal–Spatial Pattern of Acute Neuronal and Glial Loss after Spinal Cord Contusion

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12 December 2020

GeneChip analysis after acute spinal cord injury in rat

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12 December 2020

Effects of valproic acid, a histone deacetylase inhibitor, on improvement of locomotor function in rat spinal cord injury based on epigenetic science.

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12 December 2020

Serum protein binding and pharmacokinetics of valproate in man, dog, rat and mouse

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12 December 2020

Identifiers

DOI

10.1002/JNR.23200

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1 July 2019

PMC publication ID

6322559

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1 July 2019

PubMed publication ID

23404572

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1 July 2019