(Q44276073)

1 December 2017

title

Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove (English)

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1 December 2017

Ligeng Tian

1

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1 December 2017

Jane M Sayer

2

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1 December 2017

Heiko Kroth

3

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1 December 2017

Govind Kalena

4

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1 December 2017

Donald M Jerina

5

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1 December 2017

Stewart Shuman

6

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1 December 2017

language of work or name

English

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publication date

10 January 2003

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Journal of Biological Chemistry

1 December 2017

published in

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1 December 2017

volume

278

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1 December 2017

issue

11

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1 December 2017

page(s)

9905-9911

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Vaccinia virus DNA topoisomerase: a model eukaryotic type IB enzyme

1 December 2017

cites work

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A poxvirus-like type IB topoisomerase family in bacteria

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Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases

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Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

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Catalytic mechanism of DNA topoisomerase IB.

21 January 2018

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Proton relay mechanism of general acid catalysis by DNA topoisomerase IB.

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NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity

21 January 2018

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Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages

21 January 2018

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Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site

21 January 2018

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DNA duplexes containing 3'-deoxynucleotides as substrates for DNA topoisomerase I cleavage and ligation

21 January 2018

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Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions

21 January 2018

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Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167.

21 January 2018

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Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase

21 January 2018

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Effect of 2'-5' phosphodiesters on DNA transesterification by vaccinia topoisomerase

21 January 2018

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A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo

21 January 2018

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21 January 2018

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21 January 2018

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Covalent DNA binding by vaccinia topoisomerase results in unpairing of the thymine base 5' of the scissile bond.

21 January 2018

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19F NMR studies of vaccinia type IB topoisomerase. Conformational dynamics of the bound DNA substrate

21 January 2018

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21 January 2018

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Structure and function of the multifunctional DNA-repair enzyme exonuclease III

21 January 2018

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The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

21 January 2018

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X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution

21 January 2018

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Opposite stereoselective resistance to digestion by phosphodiesterases I and II of benzo[a]pyrene diol epoxide-modified oligonucleotide adducts.

21 January 2018

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Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

21 January 2018

1 reference

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O(6)-allyl protected deoxyguanosine adducts of polycyclic aromatic hydrocarbons as building blocks for the synthesis of oligonucleotides

21 January 2018

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Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M212468200

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1 December 2017

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