(Q38292238)

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Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site

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Europe PubMed Central

PubMed publication ID

1 September 2017

Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site (English)

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Europe PubMed Central

PubMed publication ID

1 September 2017

polycyclic aromatic hydrocarbons

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1

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Yves Pommier

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1 September 2017

author name string

Glenda Kohlhagen

2

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Europe PubMed Central

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1 September 2017

Gary S Laco

3

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Europe PubMed Central

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1 September 2017

Heiko Kroth

4

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Europe PubMed Central

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1 September 2017

Jane M Sayer

5

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1 September 2017

Donald M Jerina

6

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1 September 2017

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publication date

6 February 2002

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1 September 2017

number of pages

7

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Journal of Biological Chemistry

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1 September 2017

277

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1 September 2017

16

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1 September 2017

13666-13672

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Europe PubMed Central

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1 September 2017

DNA topoisomerases

1 reference

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21 January 2018

DNA topoisomerases: structure, function, and mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Topoisomerase I-mediated DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

1 reference

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21 January 2018

Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Multiple conformations of an intercalated (-)-(7S,8R,9S, 10R)-N6-[10-(7,8,9,10-tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct in the N-ras codon 61 sequence.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity

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https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

O(6)-allyl protected deoxyguanosine adducts of polycyclic aromatic hydrocarbons as building blocks for the synthesis of oligonucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Solution structure of a trans-opened (10S)-dA adduct of (+)-(7S,8R,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a fully complementary DNA duplex: evidence for a major syn conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Human topoisomerase I inhibition: docking camptothecin and derivatives into a structure-based active site model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Structural insights into the function of type IB topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Differential Poisoning of Topoisomerases by Menogaril and Nogalamycin Dictated by the Minor Groove-Binding Nogalose Sugar†

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200209200

21 January 2018

Identifiers

10.1074/JBC.M200209200

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

ResearchGate publication ID

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