(Q44319466)

1 December 2017

title

p53 mediates repression of the BRCA2 promoter and down-regulation of BRCA2 mRNA and protein levels in response to DNA damage (English)

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1 December 2017

3

Fergus J Couch

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1 December 2017

Kangjian Wu

1

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1 December 2017

Shi-Wen Jiang

series ordinal

2

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1 December 2017

language of work or name

English

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publication date

18 February 2003

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Journal of Biological Chemistry

1 December 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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1 December 2017

volume

278

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1 December 2017

issue

18

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1 December 2017

page(s)

15652-15660

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Identification of the breast cancer susceptibility gene BRCA2

1 December 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M211297200

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

21 January 2018

1 reference

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RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

21 January 2018

1 reference

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RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

21 January 2018

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

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Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

21 January 2018

1 reference

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The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

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Involvement of Brca2 in DNA repair

21 January 2018

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Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

21 January 2018

1 reference

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BRCA2 is required for homology-directed repair of chromosomal breaks

21 January 2018

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Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

21 January 2018

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BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

21 January 2018

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Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents

21 January 2018

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Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation

21 January 2018

1 reference

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage

21 January 2018

1 reference

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Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

DNA-binding activity of the transcription factor upstream stimulatory factor 1 (USF-1) is regulated by cyclin-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

Recruitment of p300/CBP in p53-dependent signal pathways

21 January 2018

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Effects of p53-expressing adenovirus on the chemosensitivity and differentiation of anaplastic thyroid cancer cells

21 January 2018

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Wild-type p53 binds to the TATA-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

p53 and SV40 T antigen bind to the same region overlapping the conserved domain of the TATA-binding protein

21 January 2018

1 reference

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Reversal of in vitro p53 squelching by both TFIIB and TFIID

21 January 2018

1 reference

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p53 down-regulates CHK1 through p21 and the retinoblastoma protein

21 January 2018

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CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling

21 January 2018

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Transcriptional cross talk between NF-kappaB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

Transcriptional activation of the F(1)F(0) ATP synthase alpha-subunit initiator element by USF2 is mediated by p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

The BRCA2 gene product functionally interacts with p53 and RAD51

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

Induction of the BRCA2 promoter by nuclear factor-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

Regulation of the human hsp70 promoter by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

p53 inhibits hypoxia-inducible factor-stimulated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211297200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211297200

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1 December 2017

1 reference