(Q44321200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Human beta-secretase activity in yeast detected by a novel cellular growth selection system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

Urs Lüthi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Claudia Schaerer-Brodbeck

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Stefan Tanner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Oliver Middendorp

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Karin Edler

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Alcide Barberis

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

publication date

1 March 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

Biochimica et Biophysica Acta

31 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

1620

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

167-178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

Alzheimer's disease: genes, proteins, and therapy

31 October 2019

cites work

1 reference

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7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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7 January 2021

A notable cleavage: winding up with beta-amyloid

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7 January 2021

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

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7 January 2021

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

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7 January 2021

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

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7 January 2021

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

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7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

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7 January 2021

Purification and cloning of amyloid precursor protein beta-secretase from human brain

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7 January 2021

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

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7 January 2021

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

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7 January 2021

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

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7 January 2021

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

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7 January 2021

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

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7 January 2021

PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae

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7 January 2021

Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase

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7 January 2021

Improved method for high efficiency transformation of intact yeast cells

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7 January 2021

The secreted form of invertase in Saccharomyces cerevisiae is synthesized from mRNA encoding a signal sequence

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7 January 2021

Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases.

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7 January 2021

Generation of amyloid beta protein from its precursor is sequence specific

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7 January 2021

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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7 January 2021

Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast

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7 January 2021

The deletion of the C-terminal tail and addition of an endoplasmic reticulum targeting signal to Alzheimer's amyloid precursor protein change its localization, secretion, and intracellular proteolysis

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7 January 2021

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

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7 January 2021

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4165%2802%2900529-9

7 January 2021

Protein localization and membrane traffic in yeast

1 reference

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7 January 2021

Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes

1 reference

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7 January 2021

The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain

1 reference

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7 January 2021

Sorting of soluble ER proteins in yeast

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7 January 2021

The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate

1 reference

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7 January 2021

Many random sequences functionally replace the secretion signal sequence of yeast invertase

1 reference

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7 January 2021

An in vivo assay for the identification of target proteases which cleave membrane-associated substrates

1 reference

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7 January 2021

Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae

1 reference

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7 January 2021

Expression and purification of correctly processed, active human TACE catalytic domain in Saccharomyces cerevisiae.

1 reference

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7 January 2021

10.1016/S0304-4165(02)00529-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595086%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference