(Q44330927)

English

Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease

scientific article published in February 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 December 2017

Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Alzheimer's disease

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reactive oxygen species

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based on heuristic

inferred from title

3

object named as

Frode Fonnum

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

author name string

Jannike M Andersen

1

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Oddvar Myhre

2

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

publication date

1 February 2003

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Neurochemical Research

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Europe PubMed Central

PubMed publication ID

2 December 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

319-326

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

https://scigraph.springernature.com/pub.10.1023/a:1022389503105

0 references

Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of microtubule-associated protein kinase after transient ischemia in the gerbil brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic acid increases activation of NADPH oxidase in monocytic U937 cells by accelerated translocation of p47-phox and co-stimulation of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of polychlorinated biphenyls on the high affinity uptake of the neurotransmitters, dopamine, serotonin, glutamate and GABA, into rat brain synaptosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor enhances glomerular mesangial cell soluble phospholipase A2 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tyrosine kinase activity of the epidermal-growth-factor receptor is necessary for phospholipase A2 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinase pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genistein, a specific inhibitor of tyrosine-specific protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Mitogen‐Activated Protein Kinase in Cultured Rat Hippocampal Neurons by Stimulation of Glutamate Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoplasmic phospholipase A2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for mitogen-activated protein kinase in cerebellar long term depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide(25-35) changes [Ca2+] in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction via the MAP kinases: proceed at your own RSK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MAPK signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction through MAP kinase cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation systems in Alzheimer's disease pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of MAP kinase in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogs of arachidonic acid methylated at C-7 and C-10 as inhibitors of leukotriene biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage is the earliest event in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mild cognitive impairment: clinical characterization and outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological stageing of Alzheimer-related changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of aliphatic, naphthenic, and aromatic hydrocarbons on production of reactive oxygen species and reactive nitrogen species in rat brain synaptosome fraction: the involvement of calcium, nitric oxide synthase, mitochondria, and phospholipa

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinase pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive glia express cytosolic phospholipase A2 after transient global forebrain ischemia in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitogen-activated protein kinase cascade mediates neurotrophic effect of epidermal growth factor in cultured rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide enhanced bradykinin-mediated inositol (1,4,5)trisphosphate formation and cytosolic free calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH oxidase contributes directly to oxidative stress and apoptosis in nerve growth factor-deprived sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic effect of L-2-chloropropionate on cultured rat cerebellar granule cells is ameliorated after inhibition of reactive oxygen species formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase A2 and its role in brain tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress induces proorphanin FQ and proenkephalin gene expression in astrocytes through p38- and ERK-MAP kinases and NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased phospholipid breakdown in schizophrenia. Evidence for the involvement of a calcium-independent phospholipase A2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immediate activator of the NADPH oxidase is arachidonate not phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regionally selective stimulation of mitogen activated protein (MAP) kinase tyrosine phosphorylation after generalized seizures in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERKs, extracellular signal-regulated MAP-2 kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor regulates TNF-alpha production in mouse macrophages via MAP kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cPLA2 is phosphorylated and activated by MAP kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of p42 mitogen-activated protein kinase as a tyrosine kinase substrate activated by maximal electroconvulsive shock in hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1022389503105

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

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