(Q44342190)

1 June 2018

title

Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists (English)

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1 June 2018

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5

Mohab M Ibrahim

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1 June 2018

Todd Vanderah

7

object named as

Todd W Vanderah

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1 June 2018

Michael H Ossipov

4

object named as

Michael H Ossipov

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1 June 2018

author name string

Shaness A Grenald

1

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1 June 2018

Madison A Young

2

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1 June 2018

Yue Wang

3

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1 June 2018

Tally M Largent-Milnes

6

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1 June 2018

language of work or name

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20 December 2016

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1 June 2018

number of pages

12

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inferred from page(s)

published in

Neuropharmacology

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1 June 2018

volume

116

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1 June 2018

page(s)

59-70

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1 June 2018

Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain

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Emergency Department Visits Involving Narcotic Pain Relievers

4 June 2018

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4 June 2018

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4 June 2018

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Microglia disrupt mesolimbic reward circuitry in chronic pain.

4 June 2018

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Use of prescription pain medications among medical cannabis patients: comparisons of pain levels, functioning, and patterns of alcohol and other drug use.

4 June 2018

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4 June 2018

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Selective monoacylglycerol lipase inhibitors: antinociceptive versus cannabimimetic effects in mice

4 June 2018

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Identification of CB₂ receptors in human nigral neurons that degenerate in Parkinson's disease.

4 June 2018

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Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice

4 June 2018

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Cannabinoids for neuropathic pain

4 June 2018

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The influence of cannabinoids on generic traits of neurodegeneration

4 June 2018

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Non-medical use of prescription opioids during the transition to adulthood: a multi-cohort national longitudinal study

4 June 2018

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Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain

4 June 2018

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Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.

4 June 2018

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Role of cannabinoid CB2 receptor in the reinforcing actions of ethanol.

4 June 2018

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Role of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine

4 June 2018

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The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice

4 June 2018

1 reference

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Nonmedical use of prescription opioids among adolescents: subtypes based on motivation for use.

4 June 2018

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Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists

4 June 2018

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The Central Role of Glia in Pathological Pain and the Potential of Targeting the Cannabinoid 2 Receptor for Pain Relief

4 June 2018

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Cannabinoid CB(2) receptor attenuates morphine-induced inflammatory responses in activated microglial cells

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice

4 June 2018

1 reference

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Central and peripheral sites of action for CB₂ receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside

4 June 2018

1 reference

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Histological studies of the effects of chronic implantation of ceramic-based microelectrode arrays and microdialysis probes in rat prefrontal cortex

4 June 2018

1 reference

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Overview of brain microdialysis

4 June 2018

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Targeting CB2 receptors and the endocannabinoid system for the treatment of pain

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Role of receptor internalization in opioid tolerance and dependence

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations

4 June 2018

1 reference

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In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models

4 June 2018

1 reference

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"Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids

4 June 2018

1 reference

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Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain.

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

An overview of drug combination analysis with isobolograms

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

State-dependent opioid control of pain

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Cardiovascular changes during morphine administration and spontaneous withdrawal in the rat

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Pharmacology of cannabinoid CB1 and CB2 receptors.

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Characterization of a rat model of incisional pain.

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Quantitative assessment of tactile allodynia in the rat paw

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Efficient analysis of experimental observations.

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Ethical guidelines for investigations of experimental pain in conscious animals

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

The formalin test: an evaluation of the method

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Potential of the cannabinoid CB(2) receptor as a pharmacological target against inflammation in Parkinson's disease.

4 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

CB2 cannabinoid receptor mediation of antinociception.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

1-(2′,4′-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5385155

CB2 cannabinoid receptor-mediated peripheral antinociception

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28007501

12 December 2020

inferred from PubMed ID database lookup

Separation of morphine analgesia from physical dependence.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28007501

12 December 2020

inferred from PubMed ID database lookup

FDA asks physicians to stop prescribing high-dose acetaminophen products

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28007501

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.NEUROPHARM.2016.12.008

1 reference

1 June 2018

PMCID

5385155

1 reference

1 June 2018

PubMed ID

28007501

1 reference

1 June 2018