(Q44356861)

2 December 2017

title

Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors (English)

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2 December 2017

Wenhui Hu

1

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2 December 2017

Zongru Guo

2

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2 December 2017

Fengming Chu

3

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2 December 2017

Aiping Bai

4

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2 December 2017

Xiang Yi

5

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2 December 2017

Guifang Cheng

6

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2 December 2017

Jing Li

7

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2 December 2017

language of work or name

English

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publication date

1 April 2003

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Bioorganic & Medicinal Chemistry

2 December 2017

published in

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2 December 2017

volume

11

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2 December 2017

issue

7

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2 December 2017

page(s)

1153-1160

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Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs

2 December 2017

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Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).

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The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor

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Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx)

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4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, valdecoxib: a potent and selective inhibitor of COX-2

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7 January 2021

Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors

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7 January 2021

1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents

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7 January 2021

2,3-Diarylcyclopentenones as orally active, highly selective cyclooxygenase-2 inhibitors

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Diarylspiro[2.4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationships

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Recent advances in inducible cyclooxygenase (COX-2) inhibition

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1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2

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7 January 2021

SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor

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7 January 2021

Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors

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7 January 2021

2,2-Dimethyl-4,5-diaryl-3(2 H )furanone derivatives as selective cyclo-oxygenase-2 inhibitors

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1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents

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7 January 2021

Selective cyclooxygenase-2 inhibitors: heteroaryl modified 1,2-diarylimidazoles are potent, orally active antiinflammatory agents

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7 January 2021

Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors

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7 January 2021

Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents

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7 January 2021

2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors

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7 January 2021

2-heterosubstituted-3-(4-methylsulfonyl)phenyl-5-trifluoromethyl pyridines as selective and orally active cyclooxygenase-2 inhibitors

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7 January 2021

Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines.

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7 January 2021

Cyclooxygenase inhibitors--current status and future prospects

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7 January 2021

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

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7 January 2021

Cyclooxygenase-2 inhibitors. Synthesis and pharmacological activities of 5-methanesulfonamido-1-indanone derivatives

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7 January 2021

Substituted heterocyclic analogs as selective COX-2 inhibitors in the flosulide class

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7 January 2021

Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

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7 January 2021

Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors

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7 January 2021

Structure-based design of COX-2 selectivity into flurbiprofen

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7 January 2021

Tracing the origins of COX-2 inhibitors' structures

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7 January 2021

Carbonyl Coupling Reactions Catalytic in Titanium and the Use of Commercial Titanium Powder for Organic Synthesis

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7 January 2021

2-Phenylindoles. Relationship between structure, estrogen receptor affinity, and mammary tumor inhibiting activity in the rat

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7 January 2021

10.1016/S0968-0896(03)00046-4

Identifiers

DOI

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2 December 2017

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