(Q44360796)

2 December 2017

Amino acid substitutions that convert the protein substrate specificity of farnesyltransferase to that of geranylgeranyltransferase type I. (English)

1 reference

2 December 2017

Del Villar K

1

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2 December 2017

Mitsuzawa H

2

1 reference

2 December 2017

Yang W

3

1 reference

2 December 2017

Sattler I

4

1 reference

2 December 2017

Tamanoi F

5

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2 December 2017

language of work or name

English

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publication date

1 January 1997

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Journal of Biological Chemistry

2 December 2017

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2 December 2017

272

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2 December 2017

1

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2 December 2017

680-687

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Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

2 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein prenylation: molecular mechanisms and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein prenylation: genes, enzymes, targets, and functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Inhibitors of Ras farnesyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Farnesyl transferase inhibitors: the successes and surprises of a new class of potential cancer chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein farnesyltransferase: production in Escherichia coli and immunoaffinity purification of the heterodimer from Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Mutant farnesyltransferase beta subunit of Saccharomyces cerevisiae that can substitute for geranylgeranyltransferase type I beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Role of SGP2, a suppressor of a gpa1 mutation, in the mating-factor signaling pathway of Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Improved method for high efficiency transformation of intact yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Structure and expression of yeast DPR1, a gene essential for the processing and intracellular localization of ras proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Protein farnesyltransferase in plants. Molecular cloning and expression of a homolog of the beta subunit from the garden pea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

KSR, a novel protein kinase required for RAS signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Mammalian protein geranylgeranyltransferase-I: substrate specificity, kinetic mechanism, metal requirements, and affinity labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Substrate characterization of the Saccharomyces cerevisiae protein farnesyltransferase and type-I protein geranylgeranyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

RHO gene products, putative small GTP-binding proteins, are important for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

Substitution of cadmium for zinc in farnesyl:protein transferase alters its substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.1.680

21 January 2018

Identifiers

DOI

10.1074/JBC.272.1.680

1 reference

2 December 2017

1 reference