(Q44371788)

2 December 2017

title

HIV-1 protease variants from 100-fold drug resistant clinical isolates: expression, purification, and crystallization (English)

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2 December 2017

John F Vickrey

1

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2 December 2017

Bradley C Logsdon

2

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2 December 2017

Gheorghe Proteasa

3

1 reference

2 December 2017

Sarah Palmer

4

1 reference

2 December 2017

Mark A Winters

5

1 reference

2 December 2017

Thomas C Merigan

6

1 reference

2 December 2017

Ladislau C Kovari

7

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2 December 2017

publication date

1 March 2003

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Protein Expression and Purification

2 December 2017

published in

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2 December 2017

volume

28

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2 December 2017

issue

1

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2 December 2017

page(s)

165-172

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https://api.crossref.org/works/10.1016%2FS1046-5928%2802%2900650-2

2 December 2017

1 reference

7 January 2021

New hope for an AIDS vaccine

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Structural and biochemical studies of retroviral proteases

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Rational approach to AIDS drug design through structural biology

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Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro

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Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural DNA.

1 reference

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Structure-based inhibitors of HIV-1 protease

1 reference

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Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: Insights into the mechanisms of drug resistance

1 reference

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Statistical potentials for fold assessment.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-5928%2802%2900650-2

7 January 2021

Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development

1 reference

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7 January 2021

Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure

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Pseudomonas aeruginosa aspartate transcarbamoylase. Characterization of its catalytic and regulatory properties

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Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors

1 reference

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Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine

1 reference

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7 January 2021

Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase

1 reference

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2',6'-Dimethylphenoxyacetyl: a new achiral high affinity P(3)-P(2) ligand for peptidomimetic-based HIV protease inhibitors

1 reference

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7 January 2021

Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases

1 reference

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7 January 2021

X-ray crystallographic studies of a series of penicillin-derived asymmetric inhibitors of HIV-1 protease

1 reference

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Structure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packing

1 reference

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Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease

1 reference

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An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease

1 reference

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7 January 2021

Structure-based design of achiral, nonpeptidic hydroxybenzamide as a novel P2/P2' replacement for the symmetry-based HIV protease inhibitors.

1 reference

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7 January 2021

Three-dimensional structures of HIV-1 and SIV protease product complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1046-5928%2802%2900650-2

7 January 2021

Structure-based design of nonpeptidic HIV protease inhibitors: the sulfonamide-substituted cyclooctylpyramones

1 reference

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7 January 2021

X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor

1 reference

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7 January 2021

Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-5928%2802%2900650-2

7 January 2021

Crystal-structure-based design and synthesis of novel C-terminal inhibitors of HIV protease

1 reference

https://api.crossref.org/works/10.1016%2FS1046-5928%2802%2900650-2

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Reverse transcriptase fidelity and HIV-1 variation

1 reference

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Differential effects of short affinity tags on the crystallization of Pyrococcus furiosus maltodextrin-binding protein

1 reference

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The HIV-1 protease as enzyme and substrate: mutagenesis of autolysis sites and generation of a stable mutant with retained kinetic properties.

1 reference

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7 January 2021

Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes

1 reference

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7 January 2021

10.1016/S1046-5928(02)00650-2

Identifiers

DOI

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2 December 2017

1 reference