(Q44374035)

English

The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo.

scientific article published in January 2003

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1 November 2019

The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo (English)

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1 November 2019

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Arianna Bellucci

4

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1 November 2019

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C Scali

1

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1 November 2019

M G Giovannini

2

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1 November 2019

C Prosperi

3

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1 November 2019

G Pepeu

5

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1 November 2019

F Casamenti

6

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1 November 2019

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1 January 2003

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1 November 2019

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1 November 2019

117

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1 November 2019

909-919

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1 November 2019

4

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1 November 2019

Oxidative damage of cardiomyocytes is limited by extracellular regulated kinases 1/2-mediated induction of cyclooxygenase-2

1 reference

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Inflammation and Alzheimer's disease

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Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals

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Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway

1 reference

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The cholinergic hypothesis of geriatric memory dysfunction

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Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.

1 reference

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Morphological, biochemical and behavioural changes induced by neurotoxic and inflammatory insults to the nucleus basalis.

1 reference

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Phosphatidylserine reverses the age-dependent decrease in cortical acetylcholine release: a microdialysis study.

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Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophages

1 reference

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7 January 2021

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Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts.

1 reference

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7 January 2021

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Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB.

1 reference

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7 January 2021

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Long-term changes in the aggregation state and toxic effects of beta-amyloid injected into the rat brain

1 reference

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7 January 2021

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NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study.

1 reference

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7 January 2021

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Microglia as mediators of inflammatory and degenerative diseases

1 reference

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7 January 2021

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Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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p38 kinase is activated in the Alzheimer's disease brain.

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ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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The selective cyclooxygenase-2 inhibitor rofecoxib reduces kainate-induced cell death in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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An investigation into the neuroprotective properties of ibuprofen

1 reference

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7 January 2021

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Interleukin-1beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

based on heuristic

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Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

based on heuristic

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Indomethacin reverses the microglial response to amyloid beta-protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

based on heuristic

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Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

based on heuristic

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Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons.

1 reference

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7 January 2021

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inferred from DOI database lookup

Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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Nonsteroidal anti-inflammatory drugs suppress T-cell activation by inhibiting p38 MAPK induction

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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inferred from DOI database lookup

Differential cellular distribution and dynamics of HSP70, cyclooxygenase-2, and c-Fos in the rat brain after transient focal ischemia or kainic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900839-4

7 January 2021

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Cognitive functions of cortical acetylcholine: toward a unifying hypothesis

1 reference

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7 January 2021

based on heuristic

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Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease.

1 reference

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inferred from DOI database lookup

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Complement activation by neurofibrillary tangles in Alzheimer's disease.

1 reference

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based on heuristic

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Cyclooxygenases 1 and 2

1 reference

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7 January 2021

based on heuristic

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Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

1 reference

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Identifiers

10.1016/S0306-4522(02)00839-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12654342%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12654342%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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