(Q44391294)

2 December 2017

title

Structure-based inhibitor discovery against adenylyl cyclase toxins from pathogenic bacteria that cause anthrax and whooping cough (English)

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2 December 2017

8

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2 December 2017

6

Milan Mrksich

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2 December 2017

Sandriyana Soelaiman

1

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2 December 2017

Binqing Q Wei

2

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2 December 2017

Pamela Bergson

3

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2 December 2017

Young-Sam Lee

4

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2 December 2017

Yuequan Shen

5

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2 December 2017

Brian K Shoichet

7

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2 December 2017

language of work or name

English

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publication date

3 April 2003

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Journal of Biological Chemistry

2 December 2017

published in

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2 December 2017

volume

278

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2 December 2017

issue

28

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2 December 2017

page(s)

25990-25997

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Anthrax as a biological weapon, 2002: updated recommendations for management

2 December 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

2001: a year of major advances in anthrax toxin research

21 January 2018

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Identification of the cellular receptor for anthrax toxin

21 January 2018

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Stoichiometry of anthrax toxin complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

Anthrax protective antigen: prepore-to-pore conversion

21 January 2018

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Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

Crystal structure of the anthrax lethal factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Crystal structure of the anthrax toxin protective antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Designing a polyvalent inhibitor of anthrax toxin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease

21 January 2018

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Screening inhibitors of anthrax lethal factor

21 January 2018

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Role of toxin functional domains in anthrax pathogenesis

21 January 2018

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Fate of germinated Bacillus anthracis spores in primary murine macrophages

21 January 2018

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Bordatella pertussis adenylate cyclase: a toxin with multiple talents

21 January 2018

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ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system

21 January 2018

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Genome sequence of Yersinia pestis, the causative agent of plague

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

Protein-protein docking with multiple residue conformations and residue substitutions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

Ligand solvation in molecular docking.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301232200

A model binding site for testing scoring functions in molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

A geometric approach to macromolecule-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Automated docking with grid-based energy evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Molecular docking using shape descriptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Matching chemistry and shape in molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Orientational sampling and rigid-body minimization in molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Purification of anthrax edema factor from Escherichia coli and identification of residues required for binding to anthrax protective antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Lead discovery using molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Kinase inhibitors: not just for kinases anymore

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells

21 January 2018

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Bacterial toxins that modify the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Molecular basis for P-site inhibition of adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Type-specific regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

High-throughput docking for lead generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Noncovalent interaction energies in covalent complexes: TEM-1 ?-lactamase and ?-lactams

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Dominant-Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Model for Aqueous Solvation Based on Class IV Atomic Charges and First Solvation Shell Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

New Class IV Charge Model for Extracting Accurate Partial Charges from Wave Functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

Substituted 1,2,3-triazolo[1,5-a]quinazolines: synthesis and binding to benzodiazepine and adenosine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301232200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301232200

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2 December 2017

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