(Q44399718)

English

Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2′-deoxyguanosine in primates

scientific article published on April 1, 2003

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scholarly article

1 reference

Europe PubMed Central

2 December 2017

Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2'-deoxyguanosine in primates (English)

1 reference

Europe PubMed Central

2 December 2017

Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2′-deoxyguanosine in primates (English)

1 reference

10.1016/S1567-5769(03)00044-4

https://api.crossref.org/works/10.1016/S1567-5769(03)00044-4

23 December 2023

1 reference

10.1016/S1567-5769(03)00044-4

https://api.crossref.org/works/10.1016/S1567-5769(03)00044-4

23 December 2023

1 reference

10.1016/S1567-5769(03)00044-4

https://api.crossref.org/works/10.1016/S1567-5769(03)00044-4

23 December 2023

Deborah A. Phillips

4

object named as

Deborah Phillips

1 reference

Europe PubMed Central

2 December 2017

author name string

J. Michael Kilpatrick

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689658

23 December 2023

Philip E. Morris

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689658

23 December 2023

David G. Serota

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689658

23 December 2023

D. Ray Moore

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689658

23 December 2023

J. Claude Bennett

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689658

23 December 2023

Y. S. Babu

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689658

23 December 2023

language of work or name

1 reference

National Center for Biotechnology Information

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23 December 2023

publication date

1 April 2003

1 reference

Europe PubMed Central

2 December 2017

full work available at URL

https://api.elsevier.com/content/article/PII:S1567576903000444?httpAccept=text/xml

1 reference

10.1016/S1567-5769(03)00044-4

https://api.crossref.org/works/10.1016/S1567-5769(03)00044-4

23 December 2023

https://api.elsevier.com/content/article/PII:S1567576903000444?httpAccept=text/plain

1 reference

10.1016/S1567-5769(03)00044-4

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23 December 2023

International Immunopharmacology

1 reference

Europe PubMed Central

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3

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Europe PubMed Central

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4

1 reference

Europe PubMed Central

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541-548

1 reference

Europe PubMed Central

2 December 2017

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

1 reference

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7 January 2021

based on heuristic

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Purine nucleoside phosphorylase. 1. Structure-function studies

1 reference

https://api.crossref.org/works/10.1016%2FS1567-5769%2803%2900044-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Purine nucleoside phosphorylase. 2. Catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1567-5769%2803%2900044-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Purine nucleoside phosphorylase. 3. Reversal of purine base specificity by site-directed mutagenesis

1 reference

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7 January 2021

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Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

1 reference

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Enzymes of the purine metabolism: inhibition and therapeutic potential

1 reference

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7 January 2021

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inferred from DOI database lookup

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Modulation of host inflammatory mediators as a treatment strategy for periodontal diseases.

1 reference

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7 January 2021

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Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

1 reference

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7 January 2021

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In vivo and in vitro pharmacologic activity of the purine nucleoside phosphorylase inhibitor BCX-34: the role of GTP and dGTP

1 reference

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Quantitative immunoassay of human deoxycytidine kinase in malignant cells

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7 January 2021

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Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues

1 reference

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Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy

1 reference

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Purine degradative enzymes in circulating malignant cells of patients with chronic B cell neoplasia

1 reference

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7 January 2021

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Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent

1 reference

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7 January 2021

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Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

1 reference

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7 January 2021

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Pharmacokinetics and pharmacodynamics of peldesine (BCX-34), a purine nucleoside phosphorylase inhibitor, following single and multiple oral doses in healthy volunteers

1 reference

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A phase III, randomized, double-blind, placebo-controlled study of peldesine (BCX-34) cream as topical therapy for cutaneous T-cell lymphoma

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Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

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Increased deoxycytidine kinase activity in cancer cells and inhibition by difluorodeoxycytidine

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23 December 2023

Identifiers

10.1016/S1567-5769(03)00044-4

1 reference

Europe PubMed Central

2 December 2017

1 reference

Europe PubMed Central

2 December 2017

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