(Q44403633)

2 December 2017

title

Identification of metabolic pathways involved in the biotransformation of tolperisone by human microsomal enzymes (English)

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.631

2 December 2017

Identification of Metabolic Pathways Involved in the Biotransformation of Tolperisone by Human Microsomal Enzymes (English)

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.631

24 December 2023

main subject

pharmaceutical science

1 reference

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.631

24 December 2023

author name string

Balázs Dalmadi

1

1 reference

2 December 2017

János Leibinger

2

1 reference

2 December 2017

Szabolcs Szeberényi

3

1 reference

2 December 2017

Tímea Borbás

4

1 reference

2 December 2017

Sándor Farkas

5

1 reference

2 December 2017

Zsolt Szombathelyi

6

1 reference

2 December 2017

Károly Tihanyi

7

1 reference

2 December 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12695352

reference URL

24 December 2023

publication date

1 May 2003

1 reference

full work available at URL

2 December 2017

https://syndication.highwire.org/content/doi/10.1124/dmd.31.5.631

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.631

Drug Metabolism and Disposition

24 December 2023

published in

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2 December 2017

volume

31

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2 December 2017

issue

5

1 reference

2 December 2017

page(s)

631-636

1 reference

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

2 December 2017

cites work

https://api.crossref.org/works/10.1124/DMD.31.5.631

2

1 reference

Genetic polymorphism in drug oxidation: in vitro studies of human debrisoquine 4-hydroxylase and bufuralol 1'-hydroxylase activities

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

3

1 reference

Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

4

1 reference

A convenient method to discriminate between cytochrome P450 enzymes and flavin-containing monooxygenases in human liver microsomes

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

5

1 reference

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

7

1 reference

Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

8

1 reference

Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

9

1 reference

Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

10

1 reference

Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

11

1 reference

Gas-liquid chromatographic method for the determination of tolperisone in human plasma: pharmacokinetic and comparative bioavailability studies

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

12

1 reference

Mass fragmentographic determination of 1-piperidino-2,4'-dimethylpropiophenone(mydocalm) by use of 1:1 mixture technique

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

13

1 reference

Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

15

1 reference

Evaluation of approach to predict the contribution of multiple cytochrome P450s in drug metabolism using relative activity factor: effects of the differences in expression levels of NADPH-cytochrome P450 reductase and cytochrome b(5) in the expressi

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

16

1 reference

Mechanisms of depressant action of muscle relaxants on spinal reflexes: participation of membrane stabilizing action

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

18

1 reference

Block of deltamethrin-modified sodium current in cultured mouse neuroblastoma cells: local anesthetics as potential antidotes

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

19

1 reference

S-Oxygenation of N-substituted thioureas catalyzed by the pig liver microsomal FAD-containing monooxygenase

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

23

1 reference

Efficacy and tolerance of repeated oral doses of tolperisone hydrochloride in the treatment of painful reflex muscle spasm: results of a prospective placebo-controlled double-blind trial

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

24

1 reference

Measurement of human liver microsomal cytochrome P450 2D6 activity using [O-methyl-14C]dextromethorphan as substrate

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

25

1 reference

Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450.

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

26

1 reference

Diethylaminoethyl 2,2-diphenylvalerate HCl (SKF 525-A)—In vivo and in vitro effects of metabolism by rat liver microsomes—Formation of an oxygenated complex

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

27

1 reference

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

28

1 reference

Direct characterization of the selectivity of furafylline as an inhibitor of human cytochromes P450 1A1 and 1A2.

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

29

1 reference

Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches.

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

30

1 reference

Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

31

1 reference

Inhibition of adrenal cytochromes P450 by 1-aminobenzotriazole in vitro. Selectivity for xenobiotic metabolism

24 December 2023

https://api.crossref.org/works/10.1124/DMD.31.5.631

32

1 reference

24 December 2023

Identifiers

DOI

10.1124/DMD.31.5.631

1 reference

2 December 2017

1 reference