(Q44410005)

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Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation.

scientific article published on 14 June 2010

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5 February 2020

Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation (English)

1 reference

Europe PubMed Central

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5 February 2020

Ahmed F. Yousef

1

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5 February 2020

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G J Fonseca

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5 February 2020

P Pelka

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5 February 2020

J N G Ablack

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5 February 2020

C Walsh

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F A Dick

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5 February 2020

D P Bazett-Jones

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5 February 2020

G S Shaw

8

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5 February 2020

J S Mymryk

9

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14 June 2010

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5 February 2020

4693-4704

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5 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2010.226

0 references

Comprehensive sequence analysis of the E1A proteins of human and simian adenoviruses.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

21 January 2018

Interaction of the E1A oncoprotein with Yak1p, a novel regulator of yeast pseudohyphal differentiation, and related mammalian kinases

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

21 January 2018

The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif

1 reference

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31 March 2020

Comparative sequence analysis of the largest E1A proteins of human and simian adenoviruses

1 reference

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31 March 2020

Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

The SUMO isopeptidase Ulp2 prevents accumulation of SUMO chains in yeast

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

CtBP, an unconventional transcriptional corepressor in development and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Common variants in the UBC9 gene encoding the SUMO-conjugating enzyme are associated with breast tumor grade

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Epigenetic reprogramming by adenovirus e1a.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Evolutionary rate in the protein interaction network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Adenovirus-5 E1A: paradox and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Concepts in sumoylation: a decade on

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Evidence for dynamically organized modularity in the yeast protein-protein interaction network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Lethality and centrality in protein networks

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Modification of proteins by ubiquitin and ubiquitin-like proteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Ubc9 sumoylation regulates SUMO target discrimination

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Identification of a substrate recognition site on Ubc9.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Specificity and stability in topology of protein networks

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Targeting Ubc9 for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Retinoblastoma protein partners

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

SUMO-targeted ubiquitin ligases in genome stability.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Molecular mimicry of SUMO promotes DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Towards a proteome-scale map of the human protein–protein interaction network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

SUMO conjugation and deconjugation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Identification of a SUMO-binding motif that recognizes SUMO-modified proteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

A human protein-protein interaction network: a resource for annotating the proteome

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

The quest for human cancer viruses.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Ubiquitin-dependent proteolytic control of SUMO conjugates

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

The Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like Modifications

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Coactivator requirements for p53-dependent transcription in the yeast Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.226

31 March 2020

Identifiers

10.1038/ONC.2010.226

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543865%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543865%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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