(Q44415145)

English

Prostate cancer cell proliferation is strongly reduced by the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in vitro on human cell lines and primary cultures

scientific article published on 4 March 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 December 2017

Prostate cancer cell proliferation is strongly reduced by the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in vitro on human cell lines and primary cultures (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Adriano Angelucci

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Adriano Angelucci

4

0 references

author name string

Carlo Vicentini

1

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Claudio Festuccia

2

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Giovanni Luca Gravina

3

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Angelo Marronaro

5

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Mauro Bologna

6

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

4 March 2003

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Journal of Cancer Research and Clinical Oncology

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

129

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

165-174

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinase inhibitors-ZD1839 (Iressa).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment options in hormone-refractory prostate cancer: current and future approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategies for the discovery of novel tyrosine kinase inhibitors with anticancer activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human primary prostate tumor cell line, ALVA‐31: A new model for studying the hormonal regulation of prostate tumor cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermittent complete androgen blockade in metastatic prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor biology (IMC-C225).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion, actin cytoskeleton organisation and the spreading of colon adenocarcinoma cells induced by EGF are mediated by alpha2beta1 integrin low clustering through focal adhesion kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen suppression of EGFR expression in breast cancer cells: a possible mechanism to modulate growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor activation in androgen-independent but not androgen-stimulated growth of human prostatic carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor mutation type III transfected into a small cell lung cancer cell line is predominantly localized at the cell surface and enhances the malignant phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoblasts modulate secretion of urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9) in human prostate cancer cells promoting migration and matrigel invasion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of epidermal growth factor signaling and activation of SRC kinase by gangliosides

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen receptor mediates the reduced tumor growth, enhanced androgen responsiveness, and selected target gene transactivation in a human prostate cancer cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bombesin stimulates growth of human prostatic cancer cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a new prostatic carcinoma cell line (TSU-Pr1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth inhibition and growth stimulation by estradiol of estrogen receptor transfected human breast epithelial cell lines involve different pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF/ErbB receptor family in ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology and cellular physiology of refractoriness to androgen ablation therapy in advanced prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of heparin binding EGF (HB-EGF), amphiregulin, TGF alpha and epiregulin in androgen-independent prostate cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(Alkylamino)methylacrylophenones: Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of flavonoids on cell cycle progression in prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of fibroblast growth factor 8, isoform b, on the biology of prostate carcinoma cells and their interaction with stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphonate-containing inhibitors of tyrosine-specific protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-erbB-2 oncoprotein content in colorectal cancer and in surrounding mucosa: relationship with clinicopathologic parameters and prognostic significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment and Characterization of a Human Primary Prostatic Adenocarcinoma Cell Line (ND-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of erbB/HER receptors, heregulin and P38 in primary breast cancer using quantitative immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical comparative analysis of transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor in normal, hyperplastic and neoplastic human prostates

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term tissue culture of prostatic carcinoma samples provides useful biological parameters related to patient prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction inhibition: changing paradigms in cancer care

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signalling by receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor-alpha and the epidermal growth factor receptor in human prostate tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TSU-Pr1 and JCA-1 cells are derivatives of T24 bladder carcinoma cells and are not of prostatic origin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ZD1839 ('Iressa') as an anticancer agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of human prostatic epithelial cells with bone marrow endothelium: binding and invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor (EGF) promotes chemomigration of a human prostate tumor cell line, and EGF immunoreactive proteins are present at sites of metastasis in the stroma of lymph nodes and medullary bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Despite activation of EGF-receptor-ERK signaling pathway, epithelial proliferation is impaired in portal hypertensive gastric mucosa: relevance of MKP-1, c-fos, c-myc, and cyclin D1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of prostate cancer chemoprevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the human androgen receptor through a protein kinase A signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aneusomy of chromosomes 7, 8, and 17 and amplification of HER-2/neu and epidermal growth factor receptor in Gleason score 7 prostate carcinoma: a differential fluorescent in situ hybridization study of Gleason pattern 3 and 4 using tissue microarray

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12712332

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-003-0420-3

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

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