(Q44417787)

2 December 2017

title

p53 expression and resistance against paclitaxel in patients with metastatic breast cancer (English)

1 reference

antineoplastic resistance

2 December 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12715164

27 December 2023

1 reference

https://api.crossref.org/works/10.1007/S00432-003-0430-1

27 December 2023

author name string

M. Schmidt

1

1 reference

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27 December 2023

A. Bachhuber

2

1 reference

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27 December 2023

A. Victor

3

1 reference

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27 December 2023

E. Steiner

4

1 reference

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27 December 2023

M. Mahlke

5

1 reference

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27 December 2023

H. A. Lehr

6

1 reference

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27 December 2023

H. Pilch

7

1 reference

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27 December 2023

W. Weikel

8

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27 December 2023

P. G. Knapstein

9

1 reference

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27 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12715164

27 December 2023

publication date

25 April 2003

1 reference

Journal of Cancer Research and Clinical Oncology

2 December 2017

published in

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2 December 2017

volume

129

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2 December 2017

issue

5

1 reference

2 December 2017

page(s)

295-302

1 reference

https://scigraph.springernature.com/pub.10.1007/s00432-003-0430-1

2 December 2017

exact match

0 references

cites work

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p53 status and the efficacy of cancer therapy in vivo

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Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione

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Prognostic value of p53, glutathione S-transferase pi, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer.

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12 December 2020

Role of specific apoptotic pathways in the restoration of paclitaxel-induced apoptosis by valspodar in doxorubicin-resistant MCF-7 breast cancer cells

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12 December 2020

Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells

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12 December 2020

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12 December 2020

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A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes

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12 December 2020

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12 December 2020

c-erbB-2 protein overexpression and p53 immunoreaction in primary and recurrent breast cancer tissues

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12 December 2020

Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin.

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12 December 2020

Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.

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12 December 2020

Substoichiometric binding of taxol suppresses microtubule dynamics.

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12 December 2020

Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer.

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12 December 2020

Assessment of molecular markers of clinical sensitivity to single-agent taxane therapy for metastatic breast cancer

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p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression

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The role of detoxifying systems in resistance of tumor cells to cisplatin and adriamycin

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Multiple forms of tubulin: different gene products and covalent modifications

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Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

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Altered expression of M beta 2, the class II beta-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance

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Tyrosine kinase inhibitor emodin suppresses growth of HER-2/neu-overexpressing breast cancer cells in athymic mice and sensitizes these cells to the inhibitory effect of paclitaxel

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12 December 2020

Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer

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12 December 2020

Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer

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12 December 2020

Overexpression of c-erbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms

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12 December 2020

Taxol-induced cell cycle arrest and apoptosis: dose-response relationship in lung cancer cells of different wild-type p53 status and under isogenic condition

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12 December 2020

E1A-mediated paclitaxel sensitization in HER-2/neu-overexpressing ovarian cancer SKOV3.ip1 through apoptosis involving the caspase-3 pathway.

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12 December 2020

Relationship of mitotic arrest and apoptosis to antitumor effect of paclitaxel

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12 December 2020

Glutathione metabolism as a determinant of therapeutic efficacy: a review

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12 December 2020

Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes.

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12 December 2020

Messenger RNA expression of resistance proteins and related factors in human ovarian carcinoma cell lines resistant to doxorubicin, taxol and cisplatin

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12 December 2020

p53-independent apoptosis induced by paclitaxel through an indirect mechanism

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12 December 2020

Construction and validation of a practical prognostic index for patients with metastatic breast cancer

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12 December 2020

P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines.

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12 December 2020

Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as front-line therapy in untreated metastatic breast cancer

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12 December 2020

Promotion of microtubule assembly in vitro by taxol

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12 December 2020

TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients

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12 December 2020

Expression of beta-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-Anticancer Drug Screen: correlation with sensitivity to microtubule active agents

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12 December 2020

Expression of drug resistance proteins in breast cancer, in relation to chemotherapy

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12 December 2020

Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas

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12 December 2020

Relationship between paclitaxel activity and pathobiology of human solid tumors

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12 December 2020

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27 December 2023

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27 December 2023

Identifiers

0 references

1 reference