(Q52826331)

8 May 2018

title

Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer. (English)

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8 May 2018

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Paraskevi Giannakakou

1

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8 May 2018

Mikhail Blagosklonny

5

object named as

Blagosklonny MV

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8 May 2018

author name string

Poy G

2

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8 May 2018

Zhan Z

3

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8 May 2018

Knutsen T

4

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8 May 2018

Fojo T

6

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8 May 2018

language of work or name

English

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publication date

1 June 2000

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8 May 2018

published in

Oncogene

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8 May 2018

volume

19

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8 May 2018

issue

27

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8 May 2018

page(s)

3078-3085

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8 May 2018

describes a project that uses

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203642

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cites work

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In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.

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Dominant-negative p53 mutations selected in yeast hit cancer hot spots

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Genetic instability and darwinian selection in tumours

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A p53-dependent mouse spindle checkpoint

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7 January 2021

Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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Abnormal centrosome amplification in the absence of p53.

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7 January 2021

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

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7 January 2021

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

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7 January 2021

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

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7 January 2021

Genetic instabilities in human cancers

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

p53 status and the efficacy of cancer therapy in vivo

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203642

7 January 2021

Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations

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7 January 2021

Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression.

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7 January 2021

Mutations in the p53 gene occur in diverse human tumour types

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7 January 2021

New colorimetric cytotoxicity assay for anticancer-drug screening

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7 January 2021

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203642

7 January 2021

An information-intensive approach to the molecular pharmacology of cancer.

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7 January 2021

The role of MAP4 expression in the sensitivity to paclitaxel and resistance to vinca alkaloids in p53 mutant cells.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203642

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8 May 2018

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8 May 2018