(Q44422893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721303%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Calpains mediate p53 activation and neuronal death evoked by DNA damage (English)

1 reference

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3 November 2019

8

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3 November 2019

author name string

Mary Sedarous

1

1 reference

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3 November 2019

Elizabeth Keramaris

2

1 reference

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3 November 2019

Michael O'Hare

3

1 reference

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3 November 2019

Edon Melloni

4

1 reference

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3 November 2019

Ruth S Slack

5

1 reference

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3 November 2019

John S Elce

6

1 reference

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3 November 2019

Peter A Greer

7

1 reference

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3 November 2019

language of work or name

English

0 references

publication date

29 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721303%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

3 November 2019

published in

1 reference

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3 November 2019

volume

278

1 reference

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3 November 2019

issue

28

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3 November 2019

page(s)

26031-26038

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721303%20AND%20SRC:MED&resulttype=core&format=json

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

3 November 2019

cites work

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Pathobiology of ischaemic stroke: an integrated view

21 January 2018

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Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

21 January 2018

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Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

21 January 2018

1 reference

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Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

21 January 2018

1 reference

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Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.

21 January 2018

1 reference

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E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Calpain: a protease in search of a function?

21 January 2018

1 reference

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Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Properties of calpastatin forms in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Modulation of cellular signals by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Degradation of transcription factors, c-Jun and c-Fos, by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Calpain inhibition: an overview of its therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Cerebellar degeneration caused by high-dose cytosine arabinoside: a clinicopathological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Etoposide induces programmed death in neurons cultured from the fetal rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Hippocampal Myc and p53 expression following transient global ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Proteolysis by calpains: a possible contribution to degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Checkpoints: How to activate p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Pretreatment with Calpain Inhibitor CEP-4143 Inhibits Calpain I Activation and Cytoskeletal Degradation, Improves Neurological Function, and Enhances Axonal Survival After Traumatic Spinal Cord Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Apoptosis in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Blockade of calpain proteolytic activity rescues neurons from glutamate excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Regulation of brain m calpain Ca2+ sensitivity by mixtures of membrane lipids: activation at intracellular Ca2+ level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

On the involvement of calpains in the degradation of the tumor suppressor protein p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302833200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302833200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721303%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference