(Q44429445)

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A Mutation in Transmembrane Domain II of the 5-Hydroxytryptamine3A Receptor Stabilizes Channel Opening and Alters Alcohol Modulatory Actions

scientific article published on May 2, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

A mutation in transmembrane domain II of the 5-hydroxytryptamine(3A) receptor stabilizes channel opening and alters alcohol modulatory actions (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

A Mutation in Transmembrane Domain II of the 5-Hydroxytryptamine3A Receptor Stabilizes Channel Opening and Alters Alcohol Modulatory Actions (English)

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

transmembrane protein

0 references

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

molecular medicine

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

author name string

Li-Xin Liu

3

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

J. S. Sessoms-Sikes

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730353

30 December 2023

Margaret E. Hamilton

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730353

30 December 2023

David M. Lovinger

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730353

30 December 2023

Tina K. Machu

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730353

30 December 2023

language of work or name

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publication date

2 May 2003

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

full work available at URL

https://syndication.highwire.org/content/doi/10.1124/jpet.103.050542

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Journal of Pharmacology and Experimental Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

306

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

595-604

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

5-HT3 receptor antagonists. An overview of their present status and future potential in cancer therapy-induced emesis

1

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Molecular Pharmacology

2

55

411

publication date

1999

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

4

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

5

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

6

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

The 5-HT3B subunit is a major determinant of serotonin-receptor function

7

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

5-HT3 receptors are membrane ion channels

8

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit

9

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors

10

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Specific decreases in ethanol- but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930.

11

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Actions of general anaesthetics on 5-HT3 receptors in N1E-115 neuroblastoma cells

12

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Attenuation of some alcohol-induced mood changes and the desire to drink by 5-HT3 receptor blockade: a preliminary study in healthy male volunteers.

13

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Zacopride, a 5-HT3 receptor antagonist, reduces voluntary ethanol consumption in rats

14

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Agonist gating and isoflurane potentiation in the human gamma-aminobutyric acid type A receptor determined by the volume of a second transmembrane domain residue.

15

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Molecular cloning, functional expression, and pharmacological characterization of 5-hydroxytryptamine3 receptor cDNA and its splice variants from guinea pig.

16

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells

17

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

21

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Molecular Pharmacology

22

48

407

publication date

1995

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Differential composition of 5-hydroxytryptamine3 receptors synthesized in the rat CNS and peripheral nervous system.

23

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Evidence for a centrally located gate in the pore of a serotonin-gated ion channel.

24

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.

26

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Mutation at the putative GABA(A) ion-channel gate reveals changes in allosteric modulation

27

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor?

28

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors.

29

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267.

30

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Molecular Pharmacology

31

50

1010

publication date

1996

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Distinct molecular basis for differential sensitivity of the serotonin type 3A receptor to ethanol in the absence and presence of agonist.

32

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Journal of Physiology

34

507.2

335

publication date

1998

1 reference

10.1124/JPET.103.050542

https://api.crossref.org/works/10.1124/JPET.103.050542

30 December 2023

Identifiers

10.1124/JPET.103.050542

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

release_iw6m3qms3je5fpfvfznyhu4pam

1 reference

https://api.fatcat.wiki/v0/release/iw6m3qms3je5fpfvfznyhu4pam

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

ResearchGate publication ID

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