(Q44432291)

English

The Alzheimer's amyloid-β(1-42) peptide forms off-pathway oligomers and fibrils that are distinguished structurally by intermolecular organization

scientific article published on 11 April 2013

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scholarly article

1 reference

Europe PubMed Central

2 December 2017

The Alzheimer's amyloid-β(1-42) peptide forms off-pathway oligomers and fibrils that are distinguished structurally by intermolecular organization (English)

1 reference

Europe PubMed Central

2 December 2017

Alzheimer's disease

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author name string

William M Tay

1

1 reference

Europe PubMed Central

2 December 2017

Danting Huang

2

1 reference

Europe PubMed Central

2 December 2017

Terrone L Rosenberry

3

1 reference

Europe PubMed Central

2 December 2017

Anant K Paravastu

4

1 reference

Europe PubMed Central

2 December 2017

language of work or name

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publication date

11 April 2013

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Europe PubMed Central

2 December 2017

Journal of Molecular Biology

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Europe PubMed Central

2 December 2017

425

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Europe PubMed Central

2 December 2017

14

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Europe PubMed Central

2 December 2017

2494-2508

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Europe PubMed Central

2 December 2017

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPINEVOLUTION: a powerful tool for the simulation of solid and liquid state NMR experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular structure of amyloid fibrils: insights from solid-state NMR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural characterization of a soluble amyloid beta-peptide oligomer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atomic View of a Toxic Amyloid Small Oligomer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiparallel -sheet architecture in Iowa-mutant -amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta aggregates formed at polar-nonpolar interfaces differ from amyloid-beta protofibrils produced in aqueous buffers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular-weight determination by light scattering

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diluting abundant spins by isotope edited radio frequency field assisted diffusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of aggregate-free, low molecular weight amyloid-beta for assembly and toxicity assays.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intersheet rearrangement of polypeptides during nucleation of {beta}-sheet aggregates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biophysical analyses of synthetic amyloid-beta(1-42) aggregates before and after covalent cross-linking. Implications for deducing the structure of endogenous amyloid-beta oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct amyloid beta-protein (Abeta) assembly pathways leading to oligomers and fibrils identified by combined fluorescence correlation spectroscopy, morphology, and toxicity analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

REPULSION, A Novel Approach to Efficient Powder Averaging in Solid-State NMR

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Symmetry-based constant-time homonuclear dipolar recoupling in solid state NMR

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new structural model of Aβ40 fibrils.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23583777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2013.04.003

1 reference

Europe PubMed Central

2 December 2017

0 references

1 reference

Europe PubMed Central

2 December 2017

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