(Q44436101)

English

No Influence of Ethnic Origin on the Pharmacokinetics and Pharmacodynamics of Melagatran Following Oral Administration of Ximelagatran, a Novel Oral Direct Thrombin Inhibitor, to Healthy Male Volunteers

scientific article published on January 1, 2003

In more languages

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

No influence of ethnic origin on the pharmacokinetics and pharmacodynamics of melagatran following oral administration of ximelagatran, a novel oral direct thrombin inhibitor, to healthy male volunteers (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

No Influence of Ethnic Origin on the Pharmacokinetics and Pharmacodynamics of Melagatran Following Oral Administration of Ximelagatran, a Novel Oral Direct Thrombin Inhibitor, to Healthy Male Volunteers (English)

1 reference

10.2165/00003088-200342050-00005

https://api.crossref.org/works/10.2165/00003088-200342050-00005

1 January 2024

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739985

1 January 2024

1 reference

10.2165/00003088-200342050-00005

https://api.crossref.org/works/10.2165/00003088-200342050-00005

1 January 2024

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

Magnus Andersson

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Gunnar Fager

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

David Gustafsson

4

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Linda C. Johansson

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739985

1 January 2024

Ulf G. Eriksson

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12739985

1 January 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12739985

1 January 2024

publication date

1 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

42

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

475-484

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.2165/00003088-200342050-00005

0 references

Antithrombotic effect of two low molecular weight thrombin inhibitors and a low-molecular weight heparin in a caval vein thrombosis model in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethnic differences in drug disposition and response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of melagatran, a new low-molecular-weight thrombin inhibitor, on thrombin and fibrinolytic enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of ethnic differences in drug disposition and response

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the oral direct thrombin inhibitor ximelagatran with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement: a phase 2 dose-finding study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ximelagatran versus warfarin for the prevention of venous thromboembolism after total knee arthroplasty. A randomized, double-blind trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, controlled, dose-guiding study of the oral direct thrombin inhibitor ximelagatran compared with standard therapy for the treatment of acute deep vein thrombosis: THRIVE I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of melagatran and the effect on ex vivo coagulation time in orthopaedic surgery patients receiving subcutaneous melagatran and oral ximelagatran: a population model analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of melagatran, a novel, direct thrombin inhibitor, in human plasma and urine by liquid chromatography-mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of creatinine clearance from serum creatinine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melagatran, an oral active-site inhibitor of thrombin, prevents or delays formation of electrically induced occlusive thrombus in the canine coronary artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of ximelagatran, a novel oral direct thrombin inhibitor, in young healthy male subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thrombin generation by the oral direct thrombin inhibitor ximelagatran in shed blood from healthy male subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ximelagatran and melagatran compared with dalteparin for prevention of venous thromboembolism after total hip or knee replacement: the METHRO II randomised trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/12739985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200342050-00005

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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